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Keywords: Rolipram
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Journal Articles
J Cell Sci (2011) 124 (13): 2253–2266.
Published: 1 July 2011
... Phosphodiesterase-4 PDE4 LIS1 Rolipram PAFAH1B1 Platelet-activating factor acetylhydrolase IB subunit α (PAFAH1B1 also known and, hereafter, referred to as LIS1) has an N-terminal coiled–coiled domain for self-association ( Ahn and Morris, 2001 ) and a C-terminal β-propeller structure formed from seven...
Journal Articles
J Cell Sci (2004) 117 (11): 2377–2388.
Published: 1 May 2004
..., such as forskolin and IBMX. In particular, by using the specific inhibitor rolipram, we identify the PDE4 family of cAMP-specific phosphodiesterases as critical regulators of this process. The effect of PDE4 on microspike formation is mediated by actions exerted through the activation of PKA – rather than through...
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