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Keywords: Retina
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Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2024) 137 (14): jcs261469.
Published: 25 July 2024
... is required for zebrafish retinal development, including Müller glia development and protection from cell death. Semaphorin Eye development Retina Reverse signaling Zebrafish National Science Foundation http://dx.doi.org/10.13039/100000001 1021795 126786 1625154 During...
Includes: Supplementary data
Journal Articles
In collection:
Cell biology and disease
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (1): jcs259187.
Published: 10 January 2022
... result in diabetic embryopathy. While many studies have examined the teratogenic effects of maternal diabetes on fetal heart development, little is known about the consequences of maternal hyperglycemia on the development of the embryonic retina. To address this question, we investigated retinal...
Includes: Supplementary data
Journal Articles
Imaging of retina cellular and subcellular structures using ptychographic hard X-ray tomography
FreeIn collection:
Imaging
Valerie Panneels, Ana Diaz, Cornelia Imsand, Manuel Guizar-Sicairos, Elisabeth Müller, Anne Greet Bittermann, Takashi Ishikawa, Andreas Menzel, Andres Kaech, Mirko Holler, Christian Grimm, Gebhard Schertler
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (19): jcs258561.
Published: 14 October 2021
... imaging with quantitative electron-density contrast. Here, we imaged, at cryogenic temperature and without sectioning, cellular and subcellular structures of a chemically fixed and stained wild-type mouse retina, including axons and synapses, with complete isotropic 3D information over tens of microns...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (7): jcs253179.
Published: 13 April 2021
...Silvia Dragoni; Bruna Caridi; Eleni Karatsai; Thomas Burgoyne; Mosharraf H. Sarker; Patric Turowski ABSTRACT Many neuronal and retinal disorders are associated with pathological hyperpermeability of the microvasculature. We have used explants of rodent retinae to study acute neurovascular...
Includes: Supplementary data
Journal Articles
Microtubule motor transport in the delivery of melanosomes to the actin-rich apical domain of the retinal pigment epithelium
Available to PurchaseMei Jiang, Antonio E. Paniagua, Stefanie Volland, Hongxing Wang, Adarsh Balaji, David G. Li, Vanda S. Lopes, Barry L. Burgess, David S. Williams
Journal:
Journal of Cell Science
J Cell Sci (2020) 133 (15): jcs242214.
Published: 4 August 2020
... ). Functional analysis of Slac2-c/MyRIP as a linker protein between melanosomes and myosin VIIa . J. Biol. Chem. 280 , 28015 - 28022 . 10.1074/jbc.M501465200 LaVail , M. M. ( 1976 ). Rod outer segment disk shedding in rat retina: relationship to cyclic lighting . Science 194 , 1071 - 1074...
Includes: Supplementary data
Journal Articles
Annexin A5 regulates surface αvβ5 integrin for retinal clearance phagocytosis
Available to Purchase
Journal:
Journal of Cell Science
J Cell Sci (2019) 132 (20): jcs232439.
Published: 16 October 2019
... that follows photoreceptor shedding in wild-type retina. Increasing ANXA5 in cells lacking αvβ5 or increasing αvβ5 in cells lacking ANXA5 does not affect particle binding. Association of cytosolic ANXA5 and αvβ5 integrin in RPE in culture and in vivo further supports their functional interdependence. Silencing...
Includes: Supplementary data
Journal Articles
Functional analyses of Pericentrin and Syne-2 interaction in ciliogenesis
Available to PurchaseIn collection:
Cilia and flagella
Nathalie Falk, Kristin Kessler, Sinja-Fee Schramm, Karsten Boldt, Elvir Becirovic, Stylianos Michalakis, Hanna Regus-Leidig, Angelika A. Noegel, Marius Ueffing, Christian T. Thiel, Ronald Roepman, Johann Helmut Brandstätter, Andreas Gießl
Journal:
Journal of Cell Science
J Cell Sci (2018) 131 (16): jcs218487.
Published: 17 August 2018
... protein and mutations in the human PCNT gene are associated with several diseases, including ciliopathies. Pcnt plays a crucial role in ciliary development in olfactory receptor neurons, but its function in the photoreceptor-connecting cilium is unknown. We downregulated Pcnt in the retina ex vivo...
Includes: Supplementary data
Journal Articles
Abscisic acid – an anti-angiogenic phytohormone that modulates the phenotypical plasticity of endothelial cells and macrophages
Available to Purchase
Journal:
Journal of Cell Science
J Cell Sci (2018) 131 (3): jcs210492.
Published: 2 February 2018
... tolerance to abiotic stresses, inhibits neovascularization by suppressing the angiogenic phenotypes of endothelial cells and macrophages, suggesting its potential usefulness in anti-angiogenic therapy. Abscisic acid Angiogenesis Retina Oxygen-induced retinopathy Hyaloid vessel Macrophage...
Includes: Supplementary data
Journal Articles
Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration
Available to PurchaseIn collection:
Cytoskeleton
Montserrat Bosch Grau, Christel Masson, Sudarshan Gadadhar, Cecilia Rocha, Olivia Tort, Patricia Marques Sousa, Sophie Vacher, Ivan Bieche, Carsten Janke
Journal:
Journal of Cell Science
J Cell Sci (2017) 130 (5): 938–949.
Published: 1 March 2017
..., is also dependent on glycylation. In contrast to many other tissues, only one glycylase, TTLL3, is expressed in retina. Ttll3 −/− mice lack glycylation in photoreceptors, which results in shortening of connecting cilia and slow retinal degeneration. Moreover, absence of glycylation results in increased...
Includes: Supplementary data
Journal Articles
RASGRF2 controls nuclear migration in postnatal retinal cone photoreceptors
Available to PurchaseIn collection:
Imaging
Journal:
Journal of Cell Science
J Cell Sci (2016) 129 (4): 729–742.
Published: 15 February 2016
...David Jimeno; Carmela Gómez; Nuria Calzada; Pedro de la Villa; Concepción Lillo; Eugenio Santos ABSTRACT Detailed immunocytochemical analyses comparing wild-type (WT), GRF1-knockout (KO), GRF2-KO and GRF1/2 double-knockout (DKO) mouse retinas uncovered the specific accumulation of misplaced...
Journal Articles
Arndt Meyer, Gerrit Hilgen, Birthe Dorgau, Esther M. Sammler, Reto Weiler, Hannah Monyer, Karin Dedek, Sheriar G. Hormuzdi
Journal:
Journal of Cell Science
J Cell Sci (2014) 127 (6): 1190–1202.
Published: 15 March 2014
...; however, the mechanisms underlying formation of Cx36-containing electrical synapses are unknown. We focus on homocellular and heterocellular gap junctions formed by an AII amacrine cell, a key interneuron found in all mammalian retinas. In mice lacking native Cx36 but expressing a variant tagged...
Includes: Supplementary data
Journal Articles
Interaction of 4.1G and cGMP-gated channels in rod photoreceptor outer segments
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Journal:
Journal of Cell Science
J Cell Sci (2013) 126 (24): 5725–5734.
Published: 15 December 2013
... complexes. Multiple splice variants of 4.1G were cloned from bovine retina. A smaller splice variant of 4.1G selectively interacted with CNG channels not associated with peripherin-2–CNG channel complex. A combination of truncation studies and domain-binding assays demonstrated that CNG channels selectively...
Journal Articles
Neuronal connexin-36 can functionally replace connexin-45 in mouse retina but not in the developing heart
Available to PurchaseMarina Frank, Britta Eiberger, Ulrike Janssen-Bienhold, Luis Pérez de Sevilla Müller, Antje Tjarks, Jung-Sun Kim, Stefan Maschke, Radoslaw Dobrowolski, Philipp Sasse, Reto Weiler, Bernd K. Fleischmann, Klaus Willecke
Journal:
Journal of Cell Science
J Cell Sci (2010) 123 (20): 3605–3615.
Published: 15 October 2010
... of the heart and in certain neurons of the retina and brain. General and cardiomyocyte-directed deficiencies of Cx45 in mice lead to lethality on embryonic day 10.5 as a result of cardiovascular defects. Neuron-directed deletion of Cx45 leads to defects in transmission of visual signals. Connexin-36 ( Cx36...
Includes: Multimedia, Supplementary data
Journal Articles
Meteorin promotes the formation of GFAP-positive glia via activation of the Jak-STAT3 pathway
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Journal:
Journal of Cell Science
J Cell Sci (2010) 123 (11): 1959–1968.
Published: 1 June 2010
... findings to the retina, and show that meteorin increases GFAP expression in Müller glia. Together, our results suggest that meteorin promotes GFAP-positive glia formation by mediating the Jak-STAT3 signaling pathway during both cortical stem cell differentiation and retinal glia development. Mouse...
Includes: Supplementary data
Journal Articles
In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction
Available to PurchaseFumitaka Osakada, Zi-Bing Jin, Yasuhiko Hirami, Hanako Ikeda, Teruko Danjyo, Kiichi Watanabe, Yoshiki Sasai, Masayo Takahashi
Journal:
Journal of Cell Science
J Cell Sci (2009) 122 (17): 3169–3179.
Published: 1 September 2009
... of development, disease and drug screening. * Author for correspondence ( [email protected] ) 19 6 2009 © The Company of Biologists Limited 2009 2009 ES cell Differentiation iPS cell Regeneration Retina Transplantation Embryonic stem (ES) cells are pluripotent cells derived...
Includes: Supplementary data
Journal Articles
Maintenance of retinal stem cells by Abcg2 is regulated by notch signaling
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Journal:
Journal of Cell Science
J Cell Sci (2007) 120 (15): 2652–2662.
Published: 1 August 2007
... , 73 -85. Ahmad, I., Dooley, C. M. and Polk, D. L. ( 1997 ). Delta-1 is a regulator of neurogenesis in the vertebrate retina. Dev. Biol. 185 , 92 -103. Ahmad, I., Dooley, C. M. and Afiat, S. ( 1998 ). Involvement of Mash1 in EGF-mediated regulation of differentiation in the vertebrate...
Includes: Supplementary data
Journal Articles
Negative regulation of retinal-neurite extension by β-catenin signaling pathway
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Journal:
Journal of Cell Science
J Cell Sci (2005) 118 (19): 4473–4483.
Published: 1 October 2005
...Yasuo Ouchi; Yoko Tabata; Ken-ichi Arai; Sumiko Watanabe Although there have been many studies on the regulation of neurite extension in mouse brain, such a mechanism in neural retina has remained to be clarified. To delineate the role of Wnt signaling in retinal development, we used a retrovirus...
Journal Articles
The apical and basal environments of the retinal pigment epithelium regulate the maturation of tight junctions during development
Available to Purchase
Journal:
Journal of Cell Science
J Cell Sci (2004) 117 (15): 3307–3318.
Published: 1 July 2004
... synergistically to promote a continuous network of tight junctions with higher electrical resistance. Independently, pituitary extract or the secretory products of either embryonic fibroblasts or the retina promoted the formation of tight junctions. In combination, three effects were identified. With basally...
Journal Articles
Molecular structure of cytoplasmic dynein 2 and its distribution in neuronal and ciliated cells
Available to PurchaseAtsushi Mikami, Sharon H. Tynan, Taro Hama, Katherine Luby-Phelps, Tetsuichiro Saito, James E. Crandall, Joseph C. Besharse, Richard B. Vallee
Journal:
Journal of Cell Science
J Cell Sci (2002) 115 (24): 4801–4808.
Published: 15 December 2002
... and in the olfactory epithelium. Antibodies to dynein 2 HC, LIC3 and a component of IFT particles strongly stained the ependymal layer lining the lateral ventricles. Both dynein 2 HC and LIC3 staining was also observed associated with connecting cilia in the retina and within primary cilia of non-neuronal cultured...
Journal Articles
The AP-3-dependent targeting of the melanosomal glycoprotein QNR-71 requires a di-leucine-based sorting signal
Available to PurchaseRoland Le Borgne, Nathalie Planque, Patrick Martin, Frédérique Dewitte, Simon Saule, Bernard Hoflack
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (15): 2831–2841.
Published: 1 August 2001
... by immunoprecipitation or by immunofluorescence. When transiently expressed in primary cultures of pigmented quail cells, E8 dissected from the pigmented layer of the retina (cells from RPE), the epitope-tagged QNR-71 was localized in dotted peripheral structures ( Fig. 2a ) that, unexpectedly, did not overlap...
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