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1-20 of 32
Keywords: Replication
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Journal Articles
In collection:
Exploring the Nucleus
Angelina Zheleva, Lola P. Camino, Nuria Fernández-Fernández, María García-Rubio, Peter Askjaer, Tatiana García-Muse, Andrés Aguilera
Journal:
Journal of Cell Science
J Cell Sci (2021) 134 (20): jcs258435.
Published: 22 October 2021
... regarding replication defects, as determined by measuring dUTP incorporation in the germline. Interestingly, this specific thp-1 mutant phenotype can be partially rescued by overexpression of RNase H. Furthermore, both mutants show a mild increase in phosphorylation of histone H3 at Ser10 (H3S10P), a mark...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2019) 132 (13): jcs228791.
Published: 1 July 2019
... and structural inheritance over successive generations. This was correlated with a major invasion deficiency at early stages of CEN2 knockdown, and replication defects at later stages. These results indicate that CEN2 is incorporated into multiple cytoskeletal structures to serve distinct functions...
Includes: Supplementary data
Journal Articles
Martina Dvořáčková, Berta Raposo, Petr Matula, Joerg Fuchs, Veit Schubert, Vratislav Peška, Bénédicte Desvoyes, Crisanto Gutierrez, Jiří Fajkus
Journal:
Journal of Cell Science
J Cell Sci (2018) 131 (2): jcs202416.
Published: 29 January 2018
... the spatiotemporal organisation of rDNA replication in Arabidopsis thaliana . To determine the subnuclear distribution of rDNA and the progression of its replication during the S phase, we apply 5-ethynyl-2′-deoxyuridine (EdU) labelling, fluorescence-activated cell sorting, fluorescence in situ hybridization...
Includes: Supplementary data
Journal Articles
In collection:
Exploring the Nucleus
Yang Han, Lvyin Wang, Jin Cui, Yu Song, Zhen Luo, Junbo Chen, Ying Xiong, Qi Zhang, Fang Liu, Wenzhe Ho, Yingle Liu, Kailang Wu, Jianguo Wu
Journal:
Journal of Cell Science
J Cell Sci (2016) 129 (24): 4534–4547.
Published: 15 December 2016
... the nucleus to the cytoplasm. More interestingly, activated SIRT1 subsequently binds with the EV71 3D pol protein (a viral RNA-dependent RNA polymerase, RdRp) to repress the acetylation and RdRp activity of 3D pol , resulting in the attenuation of viral genome replication. Moreover, SIRT1 interacts...
Includes: Supplementary data
Journal Articles
Mónica Bravo, Fabio Nicolini, Katarzyna Starowicz, Sonia Barroso, Carmela Calés, Andrés Aguilera, Miguel Vidal
Journal:
Journal of Cell Science
J Cell Sci (2015) 128 (19): 3660–3671.
Published: 1 October 2015
... replication and DNA damage repair are unclear, particularly without induced replicative stress. We have used a cellular model of conditionally inactive polycomb E3 ligases (RING1A and RING1B), which monoubiquitylate lysine 119 of histone H2A (H2AK119Ub), to examine DNA replication in unperturbed cells. We...
Includes: Supplementary data
Journal Articles
MaryClare F. Rollins, Dana M. van der Heide, Carla M. Weisend, Jean A. Kundert, Kristin M. Comstock, Elena S. Suvorova, Mario R. Capecchi, Gary F. Merrill, Edward E. Schmidt
Journal:
Journal of Cell Science
J Cell Sci (2010) 123 (14): 2402–2412.
Published: 15 July 2010
...MaryClare F. Rollins; Dana M. van der Heide; Carla M. Weisend; Jean A. Kundert; Kristin M. Comstock; Elena S. Suvorova; Mario R. Capecchi; Gary F. Merrill; Edward E. Schmidt Cells require ribonucleotide reductase (RNR) activity for DNA replication. In bacteria, electrons can flow from NADPH to RNR...
Includes: Supplementary data
Journal Articles
Leyla Kocgozlu, Philippe Lavalle, Géraldine Koenig, Bernard Senger, Youssef Haikel, Pierre Schaaf, Jean-Claude Voegel, Henri Tenenbaum, Dominique Vautier
Journal:
Journal of Cell Science
J Cell Sci (2010) 123 (1): 29–39.
Published: 1 January 2010
... stiffness plays key roles in adhesion and cytoskeletal organization, an important open question concerns the influence of substrate elasticity on replication and transcription. To answer this major question, polyelectrolyte multilayer films were used as substrate models with apparent elastic moduli ranging...
Includes: Supplementary data
Journal Articles
In collection:
Ubiquitin and Protein Degradation
Journal:
Journal of Cell Science
J Cell Sci (2009) 122 (22): 4208–4217.
Published: 15 November 2009
... is not required for the completion of mitosis, but is an important regulator of G1 phase and is required for efficient DNA replication in human and mouse somatic cells. * Author for correspondence ( stephan.geley@i-med.ac.at ) 10 9 2009 © The Company of Biologists Limited 2009 2009 FZR1...
Includes: Supplementary data
Journal Articles
Fayza Daboussi, Sylvain Courbet, Simone Benhamou, Patricia Kannouche, Malgorzata Z. Zdzienicka, Michelle Debatisse, Bernard S. Lopez
Journal:
Journal of Cell Science
J Cell Sci (2008) 121 (2): 162–166.
Published: 15 January 2008
...Fayza Daboussi; Sylvain Courbet; Simone Benhamou; Patricia Kannouche; Malgorzata Z. Zdzienicka; Michelle Debatisse; Bernard S. Lopez Faithful genome transmission requires a network of pathways coordinating DNA replication to DNA repair and recombination. Here, we used molecular combing to measure...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2007) 120 (22): 4025–4034.
Published: 15 November 2007
... by the mitochondrial genome (mtDNA). MtDNA replication is regulated by the nuclear-encoded mitochondrial transcription factor A (TFAM) and the mitochondrial-specific DNA polymerase gamma, which consists of a catalytic (POLG) and an accessory (POLG2) subunit. Differentiation of pluripotent embryonic stem cells (ESCs...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2006) 119 (12): 2621–2631.
Published: 15 June 2006
... determined that early after infection, UBF associates with the replication of viral DNA, preferentially associating with the ends of the linear viral genome, and that addition of anti-UBF serum to in vitro replication assays markedly reduced viral DNA replication. Regions of UBF important...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2006) 119 (8): 1483–1493.
Published: 15 April 2006
... correlated with aberrant localisation of initiation of DNA replication within the nucleus and an increased fraction of cells in mitosis. Chromosomal fragmentation and other aberrations, including shorter, thicker chromatids, end-to-end fusion, and loss of a chromatid, suggest that reduced B-Myb activity...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2006) 119 (1): 124–131.
Published: 1 January 2006
...Maria A. Marchetti; Martin Weinberger; Yota Murakami; William C. Burhans; Joel A. Huberman Previous studies have indicated that replication stress can trigger apoptosis-like cell death, accompanied (where tested) by production of reactive oxygen species (ROS), in mammalian cells and budding yeast...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2004) 117 (22): 5303–5312.
Published: 15 October 2004
...Noriaki Shimizu; Kenta Shingaki The chromosomal G/R bands are alternating domains differing in their nucleotide sequence biases. The bands are also related to the time of replication: pulse-labeling during S phase makes the replication sites as visible as replication bands that are close to the G/R...
Journal Articles
Marion Ritzi, Kristina Tillack, Jeannine Gerhardt, Elisabeth Ott, Sibille Humme, Elisabeth Kremmer, Wolfgang Hammerschmidt, Aloys Schepers
Journal:
Journal of Cell Science
J Cell Sci (2003) 116 (19): 3971–3984.
Published: 1 October 2003
...Marion Ritzi; Kristina Tillack; Jeannine Gerhardt; Elisabeth Ott; Sibille Humme; Elisabeth Kremmer; Wolfgang Hammerschmidt; Aloys Schepers The sequential binding of the origin recognition complex (ORC), Cdc6p and the minichromosome maintenance proteins (MCM2-7) mediates replication competence...
Journal Articles
Kazuhiro Furukawa, Shin Sugiyama, Shinichi Osouda, Hidemasa Goto, Masaki Inagaki, Tsuneyoshi Horigome, Saburo Omata, Maeve McConnell, Paul A. Fisher, Yasuyoshi Nishida
Journal:
Journal of Cell Science
J Cell Sci (2003) 116 (18): 3811–3823.
Published: 15 September 2003
... of Biologists Limited 2003 2003 BAF Cell cycle Lamin Nuclear envelope Chromosome Replication The nuclear envelope (NE) is continuous with the endoplasmic reticulum (ER) and forms the boundary between the nucleus and cytoplasm. It also participates in the arrangement of chromosomes...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (11): 2015–2025.
Published: 1 June 2001
... of a role for chaperones in DNA replication in higher eukaryotes. *Author for correspondence (e-mail: s.cotterill@sghms.ac.uk ) ‡ These authors contributed equally to this paper 10 3 2001 © The Company of Biologists Limited 2001 2001 Replication Heat shock proteins DNA...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (4): 747–750.
Published: 15 February 2001
...Jan Mal ínský; Karel Koberna; David Stan ěk; Martin Ma šata; Ivan Votruba; Ivan Ra ška ABSTRACT Earlier studies have established that the average speed of a replication fork is two to three times slower in early S-phase than in late S-phase and that the intracellular 2′-deoxyribonucleoside 5...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2000) 113 (15): 2647–2658.
Published: 1 August 2000
... the progression through an individual assembly reaction to its active participation in a marking system. This marking system could be exploited at the crossroads of DNA replication and repair to monitor genome integrity and to define particular epigenetic states. * Author for correspondence (e...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (1999) 112 (19): 3215–3224.
Published: 1 October 1999
... progression into S phase. Our results indicate that growth inhibition correlates with disruption of the nuclear morphology which seems to modify the intranuclear network required during the early steps of DNA replication. We report that a mutant encoding a protein deleted from the central domain of kin17...
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