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Keywords: Regeneration
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Journal Articles
J Cell Sci (2024) 137 (4): jcs261655.
Published: 23 February 2024
... comparisons between plant and animal studies. Autophagy Plant science Regeneration Reprogramming Somatic reprogramming Stem cells Danmarks Frie Forskningsfond http://dx.doi.org/10.13039/501100011958 DFF1-1032-00249B Novo Nordisk Fonden http://dx.doi.org/10.13039/501100009708...
Journal Articles
J Cell Sci (2023) 136 (15): jcs260987.
Published: 31 July 2023
... cues into biochemical and transcriptional adaptation (i.e. mechanotransduction) across tissues. Here, we discuss the recent insights into the roles of hemidesmosomes in age-related tissue regeneration and aging in C. elegans , mice and humans. We highlight the emerging concept of preserved dynamic...
Journal Articles
Journal Articles
J Cell Sci (2022) 135 (4): jcs256008.
Published: 21 February 2022
...Megha Agarwal; Anushree Bharadwaj; Sam J. Mathew ABSTRACT Muscle stem (satellite) cells express Pax7, a key transcription factor essential for satellite cell maintenance and adult muscle regeneration. We identify the corepressor transducin-like enhancer of split-4 (TLE4) as a Pax7 interaction...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (1): jcs258694.
Published: 12 January 2022
... expression and spatial localization of collagen XI was studied following injury in a Col11a1 inducible knockout mouse model. We found that collagen XI expression occurs during early maturation and is upregulated after stromal injury in areas of regeneration and remodeling. Abnormal fibrillogenesis with new...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (12): jcs242297.
Published: 19 June 2020
...Osvaldo Contreras; Hesham Soliman; Marine Theret; Fabio M. V. Rossi; Enrique Brandan ABSTRACT Mesenchymal stromal cells (MSCs) are multipotent progenitors essential for organogenesis, tissue homeostasis, regeneration and scar formation. Tissue injury upregulates transforming growth factor β (TGF-β...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (8): jcs237545.
Published: 24 April 2020
...Annelies Wouters; Jan-Pieter Ploem; Sabine A. S. Langie; Tom Artois; Aziz Aboobaker; Karen Smeets ABSTRACT Pluripotent stem cells hold great potential for regenerative medicine. Increased replication and division, such is the case during regeneration, concomitantly increases the risk of adverse...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (22): jcs231993.
Published: 14 November 2019
... they potentiate osteoblast differentiation and bone formation. Here, we use zebrafish caudal fin regeneration as a model to clarify how the Hippo pathway regulates de novo bone formation and osteoblast differentiation. We demonstrate that Yap inhibition leads to accumulation of osteoprogenitors and prevents...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (19): jcs232157.
Published: 9 October 2019
...Osvaldo Contreras; Meilyn Cruz-Soca; Marine Theret; Hesham Soliman; Lin Wei Tung; Elena Groppa; Fabio M. Rossi; Enrique Brandan ABSTRACT Fibro–adipogenic progenitors (FAPs) are tissue-resident mesenchymal stromal cells (MSCs) required for proper skeletal muscle development, regeneration...
Includes: Supplementary data
Journal Articles
In collection:
Metabolism
J Cell Sci (2018) 131 (14): jcs212977.
Published: 27 July 2018
...Francesca Pala; Daniela Di Girolamo; Sébastien Mella; Siham Yennek; Laurent Chatre; Miria Ricchetti; Shahragim Tajbakhsh ABSTRACT During growth, homeostasis and regeneration, stem cells are exposed to different energy demands. Here, we characterise the metabolic pathways that mediate the commitment...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (2): jcs208215.
Published: 29 January 2018
... valuable tools to increase crop regeneration and transformation efficiency. References Aida , M. , Beis , D. , Heidstra , R. , Willemsen , V. , Blilou , I. , Galinha , C. , Nussaume , L. , Noh , Y.-S. , Amasino , R. and Scheres , B. ( 2004 ). The PLETHORA...
Journal Articles
J Cell Sci (2017) 130 (17): 2833–2842.
Published: 1 September 2017
... muscles being more prone to spontaneous regeneration. When the regeneration capacity of the compromised NesKO muscle was tested by muscle injury experiments, a significant healing delay was observed. NesKO satellite cells showed delayed proliferation kinetics in conjunction with an elevation in p35...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (11): 1917–1928.
Published: 1 June 2017
... signaling. Wound repair Regeneration Cell migration Epidermis Giant cell Ministry of Education, Science and Technology 10.13039/501100004085 NRF-2012R1A1A2044919 NRF-2015R1A2A2A01006660 Yonsei University 10.13039/501100002573 Cell–cell fusion elicits dramatic...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (2): 332–343.
Published: 15 January 2017
...Masahiko Takemura; Hiroshi Nakato ABSTRACT Stem cell division is activated to trigger regeneration in response to tissue damage. The molecular mechanisms by which this stem cell mitotic activity is properly repressed at the end of regeneration are poorly understood. Here, we show that a specific...
Includes: Supplementary data
Journal Articles
In collection:
Metabolism
J Cell Sci (2015) 128 (24): 4467–4474.
Published: 15 December 2015
... underlying our understanding of stem cell quiescence that can be attributed to studies in yeast. Quiescence Metabolism Yeast Adult stem cell Signaling pathways Regeneration A distinguishing feature of stem cells is their ability to retain the primal capacity to generate more stem cells...
Journal Articles
Journal Articles
J Cell Sci (2014) 127 (21): 4543–4548.
Published: 1 November 2014
... cells remain in a dormant quiescent state in uninjured muscle, they are poised to activate and produce committed progeny. Unlike committed myogenic progenitor cells, the self-renewal capacity gives muscle stem cells the ability to engraft as satellite cells and capitulate long-term regeneration. Similar...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (3): 599–608.
Published: 1 February 2014
...-injury-induced regeneration in Sharp-1-deficient mice. We show that embryonic skeletal muscle development is not impaired in the absence of Sharp-1; however, post-natally, the regenerative capacity is compromised. Although the initial phases of injury-induced regeneration proceed normally in Sharp-1...
Journal Articles
J Cell Sci (2013) 126 (5): 1122–1133.
Published: 1 March 2013
... of PAK18, modulating PAK function using cell-permeable peptides may be a useful strategy to enhance axon regeneration after injury. PAK is implicated in axon guidance downstream of both attractive and repulsive cues ( Aizawa et al., 2001 ; Fan et al., 2003 ; Lucanic et al., 2006 ; Shekarabi et al...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (1): 90–102.
Published: 1 January 2013
.... * Author for correspondence ( [email protected] ). 10 10 2012 © 2013. Published by The Company of Biologists Ltd 2013 RNA transport Axon growth Axonal protein synthesis Regeneration Polarized eukaryotic cells transport mRNAs from the nucleus to subcellular domains...
Includes: Supplementary data