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Keywords: Rab40b
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Journal Articles
The role and regulation of Rab40b–Tks5 complex during invadopodia formation and cancer cell invasion
Open AccessIn collection:
Cell migration
Journal:
Journal of Cell Science
J Cell Sci (2016) 129 (23): 4341–4353.
Published: 1 December 2016
...Abitha Jacob; Erik Linklater; Brian A. Bayless; Traci Lyons; Rytis Prekeris ABSTRACT Invadopodia formation and extracellular matrix degradation are key events during cancer cell invasion, yet little is known about mechanisms mediating these processes. Here, we report that Rab40b plays a key role...
Includes: Supplementary data
Journal Articles
Abitha Jacob, Jian Jing, James Lee, Pepper Schedin, Simon M. Gilbert, Andrew A. Peden, Jagath R. Junutula, Rytis Prekeris
Journal:
Journal of Cell Science
J Cell Sci (2013) 126 (20): 4647–4658.
Published: 15 October 2013
... to the invadopodia during cancer cell invasion remains to be defined. Because Rab GTPases are key regulators of membrane transport, we screened a human Rab siRNA library and identified Rab40b GTPase as a protein required for secretion of MMP2/9. We also have shown that Rab40b functions during at least two distinct...
Includes: Supplementary data
