...Jesica Diaz-Vera; Sarah Palmer; Juan Ramon Hernandez-Fernaud; Emmanuel Dornier; Louise E. Mitchell; Iain Macpherson; Joanne Edwards; Sara Zanivan; Jim C. Norman ABSTRACT We have previously shown that Rab17, a small GTPase associated with epithelial polarity, is specifically suppressed by ERK2 (also...

... not moving. Using gene expression arrays we found that the expression of the genes for Rab17 and liprin-β2 was increased by knockdown of ERK2 and restored to normal levels following re-expression of ERK2, but not ERK1. Both play inhibitory roles in the invasive behaviour of three independent cancer cell...