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Keywords: ROS
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Journal Articles
J Cell Sci (2020) 133 (23): jcs250944.
Published: 9 December 2020
... of ATPsynβ (a Complex V subunit), which produces higher levels of reactive oxygen species (ROS) than pdsw knockdown, instead synergizes with Hipk to potentiate JNK activation and the downstream induction of matrix metalloproteinases. Accordingly, ATPsynβ knockdown suppresses Hipk-induced tumor-like growth...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (5): jcs236471.
Published: 2 March 2020
... 2020 © 2020. Published by The Company of Biologists Ltd 2020 http://www.biologists.com/user-licence-1-1/ Summary: Here, we explore how the deformability of macrophages impact their phagocytic ability and report a ROS-dependent cytoplasmic stiffening that reduces their phagocytic...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2018) 131 (7): jcs212233.
Published: 10 April 2018
... of the daughter cell mass within the mother cell wall at cytokinesis. Differential desiccation tolerance across the five species, assessed from photosynthetic efficiency during desiccation/rehydration cycles, was accompanied by differential accumulation of intracellular reactive oxygen species (ROS) detected...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (15): 2925–2936.
Published: 1 August 2016
... exposed to high glucose, which overexpressed and secreted active TGF-β1, Arg protein and activity was downregulated. A further TGF-β1 increase was induced by Arg silencing with siRNA, as with the Arg tyrosine kinase inhibitor Imatinib. In the cells exposed to high glucose, reactive oxygen species (ROS...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (1): 155–165.
Published: 1 January 2016
.... , Morcos , F. , et al. ( 2015 ). Structure–function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease . Biochim. Biophys. Acta   1853 , 1294 - 1315 . 10.1016/j.bbamcr.2014.10.014 Torti , S. V. and Torti , F. M...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (16): 2989–2995.
Published: 15 August 2015
...Carlos Wilson; M. Tulio Núñez; Christian González-Billault ABSTRACT Reactive oxygen species (ROS) produced by the NADPH oxidase (NOX) complex play important physiological and pathological roles in neurotransmission and neurodegeneration, respectively. However, the contribution of ROS...
Includes: Supplementary data
Journal Articles
In collection:
Metabolism
J Cell Sci (2014) 127 (22): 4954–4963.
Published: 15 November 2014
... interests. 28 05 2014 19 09 2014 © 2014. Published by The Company of Biologists Ltd 2014 Mitochondrial fusion Metabolic stress HDAC6 MFN1 ROS Acetylation The ability to use a diverse set of fuel sources in response to changing nutrient environments is crucial...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (17): 3862–3872.
Published: 1 September 2013
... laboratory fish species Japanese medaka. Here, pigment cells are transformed by an oncogenic receptor tyrosine kinase in fish expressing GFP throughout their vasculature. We show that angiogenesis occurs in a reactive oxygen species (ROS)- and NF-κB-dependent, but hypoxia-independent manner. Intriguingly, we...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2012) 125 (9): 2115–2125.
Published: 1 May 2012
.... * These authors contributed equally to this work ‡ Authors for correspondence ( filomini@bio.uniroma2.it ; ciriolo@bio.uniroma2.it ) © 2012. 2012 ROS Apoptosis Autophagy Nitric oxide Living organisms derive energy from the breakdown of the molecular bonds of nutrients, and then convert...
Journal Articles
Journal Articles
J Cell Sci (2011) 124 (11): 1911–1924.
Published: 1 June 2011
... of Myc by a mechanism not previously reported in normal lung fibroblasts. We also show that reactive oxygen species (ROS) derived from steady-state Romo1 expression are necessary for cell cycle entry of quiescent cells. From this study, we suggest that the generation of ROS mediated by pre-existing Romo1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (17): 2901–2913.
Published: 1 September 2010
... growth-factor deprivation. Serum starvation stimulates the catalytic activity and Y311 phosphorylation of PKCδ through reactive oxygen species (ROS) and the Src family kinases. Mutation of PKCδ at Y311 and Y322, both of which are phosphorylation sites for Src, impairs its activation and ability...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (6): 917–926.
Published: 15 March 2010
... by downregulation of the expression of Fis1 and Drp1, two proteins regulating mitochondrial fission. Targeted photodamage of mitochondria induced the formation of reactive oxygen species (ROS), which triggered mitochondrial fragmentation and loss of membrane potential in young cells, whereas senescent cells proved...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (19): 3522–3530.
Published: 1 October 2009
...Simone Lipinski; Andreas Till; Christian Sina; Alexander Arlt; Helmut Grasberger; Stefan Schreiber; Philip Rosenstiel Generation of microbicidal reactive oxygen species (ROS) is a pivotal protective component of the innate immune system in many eukaryotes. NOD (nucleotide oligomerisation domain...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (8): 1238–1247.
Published: 15 April 2009
.... * Author for correspondence (e-mail: uknaus@scripps.edu ) 13 12 2008 © The Company of Biologists Limited 2009 2009 NADPH oxidase Duox ROS Lung epithelial cells Migration Regulated generation of reactive oxygen species (ROS) has been the hallmark of phagocytes...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2009) 122 (7): 919–928.
Published: 1 April 2009
...Catherine F. Cowell; Heike Döppler; Irene K. Yan; Angelika Hausser; Yoshio Umezawa; Peter Storz Increases in reactive oxygen species (ROS) have been implicated in age-related diseases, including cancer. The serine/threonine kinase protein kinase D1 (PKD1) is a stress-responsive kinase and sensor...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (5): 706–715.
Published: 1 March 2009
... plays a physiological role in the differentiation of yeast colonies by facilitating elaboration of distinct zones of cell death. * Author for correspondence (e-mail: c.w.gourlay@kent.ac.uk ) 3 11 2008 © The Company of Biologists Limited 2009 2009 PKA ROS Ras Actin...