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Keywords: RNA Polymerase II
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Journal Articles
J Cell Sci (2018) 131 (8): jcs211094.
Published: 13 April 2018
.... ( 2015 ). Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation . BMC Biol.   13 , 35 . 10.1186/s12915-015-0147-z Aronova , M. A. and Leapman , R. D. ( 2012 ). Development of electron energy-loss spectroscopy...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (18): 3412–3425.
Published: 15 September 2016
... surrounds the absence of classical actin filaments in the nucleus. To address this question, we investigated how polymerizing nuclear actin into persistent nuclear actin filaments affected transcription by RNA polymerase II. Nuclear filaments impaired nuclear actin dynamics by polymerizing and sequestering...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (12): 2085–2093.
Published: 15 June 2010
...-immunoprecipitated with human RNA polymerase II from mitotic cell extracts and identified U1 small nuclear RNA (snRNA) as a major species. To investigate a possible splicing-independent recruitment of U1 snRNA to transcription units, we established cell lines having integrated a reporter gene containing a functional...
Journal Articles
J Cell Sci (2009) 122 (9): 1275–1284.
Published: 01 May 2009
... and RNA polymerase II. We propose that CTCF interacts with one or two different partners according to the biological context, applying the Roman principle of governance, `divide and rule' (divide et impera). * Author for correspondence (e-mail: jordanka@uwyo.edu ) © The Company of Biologists...
Journal Articles
J Cell Sci (2009) 122 (9): 1418–1429.
Published: 01 May 2009
... formation, for RNA transcription, splicing and ribosome biogenesis, for chromatin silencing, for biosynthesis of lipids and ATP, for cell-wall and membrane morphogenesis, and for protein trafficking and vesicle fusion. We specifically highlight Fcp1, a CTD phosphatase of RNA polymerase II, which...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (8): 1275–1283.
Published: 15 April 2008
...Alexandre E. Escargueil; Virginie Poindessous; Daniele Grazziotin Soares; Alain Sarasin; Peter R. Cook; Annette K. Larsen Transcription-coupled repair (TCR) plays a key role in the repair of DNA lesions induced by bulky adducts and is initiated when the elongating RNA polymerase II (Pol II) stalls...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (9): 1689–1700.
Published: 01 May 2007
... with the chromatin, which is not yet condensing during these stages [for a scheme of chromatin distribution based on EM studies, see Fuller ( Fuller, 1993 )]. The late canoe stage is the only post-meiotic stage where we find distinct regions of RNA polymerase II with an antibody directed against a phosphorylated...
Journal Articles
J Cell Sci (2003) 116 (3): 447–451.
Published: 01 February 2003
...Jesper Q. Svejstrup In the past few months, several discoveries relating to the mechanism underlying transcription-coupled DNA repair (TCR) have been reported. These results make it timely to propose a hypothesis for how eukaryotic cells might deal with arrested RNA polymerase II (Pol II) complexes...
Journal Articles
J Cell Sci (2002) 115 (22): 4275–4284.
Published: 15 November 2002
.... These results indicate that Mat1 is not essential for the transcriptional program underlying the myelination of peripheral axons by Schwann cells and suggest that the function of Mat1 in RNA polymerase II-mediated transcription in these cells is regulatory rather than essential. ‡ Author...
Journal Articles
J Cell Sci (2002) 115 (20): 3865–3871.
Published: 15 October 2002
...Karla M. Neugebauer Intense research in recent years has shown that many pre-mRNA processing events are co-transcriptional or at least begin during RNA synthesis by RNA polymerase II (Pol II). But is it important that pre-mRNA processing occurs co-transcriptionally? Whereas Pol II directs 5...
Journal Articles
J Cell Sci (2002) 115 (2): 321–328.
Published: 15 January 2002
... time, throughout the nucleoplasm. Inhibition of RNA polymerase II activity resulted in a rapid decrease in the number of transcripts in the nuclear RNA foci (half time ∼two minutes), indicating that accumulated transcripts were rapidly spliced and then released. The dispersed nucleoplasmic transcripts...
Journal Articles
J Cell Sci (2001) 114 (14): 2591–2603.
Published: 15 July 2001
... stain nuclei in a speckled pattern, overlapping with spliceosome components and the hyperphosphorylated form of RNA polymerase II. Like RNA polymerase II, CrkRS is a constitutive MPM-2 antigen throughout the cell cycle. Anti-CrkRS immunoprecipitates phosphorylate the C-terminal domain of RNA polymerase...
Journal Articles
J Cell Sci (2001) 114 (13): 2501–2511.
Published: 01 July 2001
... and pre-mRNA processing machinery, including RNA polymerase II and the splicing factor SC-35. Immunodepletion and add-back experiments demonstrate that PtdIns(4,5) P 2 and associated factors are necessary but not sufficient for pre-mRNA splicing in vitro, indicating a crucial role for PtdIns(4,5) P 2...