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Keywords: RARα
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Journal Articles

TRIM32 promotes neural differentiation through retinoic acid receptor-mediated transcription

In collection:
Proteostasis
Tomonobu Sato, Fumihiko Okumura, Satoshi Kano, Takeshi Kondo, Tadashi Ariga, Shigetsugu Hatakeyama
Journal: Journal of Cell Science
J Cell Sci (2011) 124 (20): 3492–3502.
https://doi.org/10.1242/jcs.088799
Published: 15 October 2011
... activation. Ubiquitinylation, which is one of the post-translational modifications, appears to be involved in the transcriptional activity of intranuclear receptors including retinoic acid receptor α (RARα). Mutations in the tripartite motif-containing protein 32 gene ( TRIM32 ; also known as E3 ubiquitin...
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Includes: Supplementary data
Journal Articles

Dynamics of component exchange at PML nuclear bodies

Stefanie Weidtkamp-Peters, Thorsten Lenser, Dmitri Negorev, Norman Gerstner, Thomas G. Hofmann, Georg Schwanitz, Christian Hoischen, Gerd Maul, Peter Dittrich, Peter Hemmerich
Journal: Journal of Cell Science
J Cell Sci (2008) 121 (16): 2731–2743.
https://doi.org/10.1242/jcs.031922
Published: 15 August 2008
... times faster at NBs than PML proteins. Turnover dynamics of PML and SP100 at NBs is modulated by SUMOylation. Exchange is not temperature-dependent but depletion of cellular ATP levels induces protein immobilization at NBs. The PML-RARα oncogene exhibits a strong NB retention effect on wild-type PML...
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Includes: Supplementary data