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Keywords: Quiescence
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Journal Articles
In collection:
Stem cells
J Cell Sci (2023) 136 (24): jcs261200.
Published: 27 December 2023
...Margaret Hung; Hsiao-Fan Lo; Grace E. L. Jones; Robert S. Krauss ABSTRACT Skeletal muscle stem cells (MuSCs, also called satellite cells) are the source of the robust regenerative capability of this tissue. The hallmark property of MuSCs at homeostasis is quiescence, a reversible state of cell...
Includes: Supplementary data
Journal Articles
In collection:
Cell cycle , Polarity
J Cell Sci (2023) 136 (19): jcs261178.
Published: 11 October 2023
...Rebeka Tomasin; Ana Maria Rodrigues; Antonio Carlos Manucci; Alexandre Bruni-Cardoso ABSTRACT Cell context is key for cell state. Using physiologically relevant models of laminin-rich extracellular matrix (lrECM) induction of mammary epithelial cell quiescence and differentiation, we provide...
Includes: Supplementary data
Journal Articles
In collection:
Cell cycle , Metabolism
J Cell Sci (2023) 136 (16): jcs260787.
Published: 15 August 2023
...Yipeng Du; Parul Gupta; Shenlu Qin; Matthew Sieber ABSTRACT Cellular quiescence is a dormant, non-dividing cell state characterized by significant shifts in physiology and metabolism. Quiescence plays essential roles in a wide variety of biological processes, ranging from microbial sporulation...
Journal Articles
In collection:
Cell cycle , Metabolism
J Cell Sci (2023) 136 (10): jcs260727.
Published: 25 May 2023
... significantly smaller ( Fig. 1 B–D; Fig. S1D–F ), as seen in quiescence induced by nitrogen starvation ( Sajiki et al., 2009 ; Su et al., 1996 ). The nuclear and chromosomal sizes continued to decrease for at least 1 day after entry into stationary phase, and the nuclear size became less than one third...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (9): jcs260454.
Published: 5 May 2023
... – the primary cilium – as a sensory antenna, have since been extensively studied, but the role of the cilium–centrosome axis in cell fate is still emerging. In this Opinion piece, we view cellular quiescence and tissue homeostasis from the vantage point of the cilium–centrosome axis. We focus on a less explored...
Journal Articles
Journal Articles
In collection:
Stem cells
J Cell Sci (2022) 135 (4): jcs256008.
Published: 21 February 2022
... commitment. Our results indicate that TLE4 represses Pax7-mediated Myf5 transcriptional activation by occupying the −111 kb Myf5 enhancer to maintain quiescence. Loss of TLE4 function causes Myf5 upregulation, an increase in satellite cell numbers and altered differentiation dynamics during regeneration...
Includes: Supplementary data
Journal Articles
In collection:
Polarity
J Cell Sci (2019) 132 (10): jcs223313.
Published: 16 May 2019
... as TJP2) in the polarized epithelium. The distribution of Cx43 is altered by pro-inflammatory breast cancer risk factors such as leptin and high-fat diet, as shown in cell culture and on tissue biopsy sections. The control of polarity-mediated quiescence and MSO may contribute to the tumor-suppressive...
Includes: Supplementary data
Journal Articles
In collection:
Polarity
J Cell Sci (2019) 132 (10): jcs223313.
Published: 16 May 2019
... as TJP2) in the polarized epithelium. The distribution of Cx43 is altered by pro-inflammatory breast cancer risk factors such as leptin and high-fat diet, as shown in cell culture and on tissue biopsy sections. The control of polarity-mediated quiescence and MSO may contribute to the tumor-suppressive...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (1): jcs213025.
Published: 2 January 2019
...Isabelle Sagot; Damien Laporte ABSTRACT Most cells, from unicellular to complex organisms, spend part of their life in quiescence, a temporary non-proliferating state. Although central for a variety of essential processes including tissue homeostasis, development and aging, quiescence is poorly...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (23): jcs216804.
Published: 30 November 2018
... use transformed cells, but the majority of cells in an adult organism have exited the cell cycle. Here, we review endocytosis in dividing, quiescent and terminally differentiated cells. Endocytosis Clathrin-mediated endocytosis Clathrin-independent endocytosis Cell cycle Mitosis Quiescence...
Journal Articles
J Cell Sci (2018) 131 (23): jcs216804.
Published: 30 November 2018
... use transformed cells, but the majority of cells in an adult organism have exited the cell cycle. Here, we review endocytosis in dividing, quiescent and terminally differentiated cells. Endocytosis Clathrin-mediated endocytosis Clathrin-independent endocytosis Cell cycle Mitosis Quiescence...
Journal Articles
In collection:
Metabolism , Stem cells
J Cell Sci (2015) 128 (24): 4467–4474.
Published: 15 December 2015
... such example, the quiescent adult mammalian stem cell, and examines concepts underlying our understanding of quiescence that can be attributed to studies in yeast. We discuss the metabolic, signaling and gene regulatory events that control entry and exit into quiescence in yeast. These processes and events...
Journal Articles
In collection:
Metabolism
J Cell Sci (2015) 128 (24): 4467–4474.
Published: 15 December 2015
... such example, the quiescent adult mammalian stem cell, and examines concepts underlying our understanding of quiescence that can be attributed to studies in yeast. We discuss the metabolic, signaling and gene regulatory events that control entry and exit into quiescence in yeast. These processes and events...
Journal Articles
J Cell Sci (2007) 120 (17): 3086–3098.
Published: 1 September 2007
...-mail: jdhawan@ccmb.res.in ) 25 6 2007 © The Company of Biologists Limited 2007 2007 mDia1 MyoD SRF RhoA Adhesion-dependent signaling Quiescence Synchronized myoblasts β-catenin TCF APC Skeletal muscle formation occurs through a series of regulated events involving...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (5): 737–747.
Published: 1 March 2007
... phase in proliferating cells and upon cell cycle exit in quiescence, senescence and differentiation. Upon cell cycle exit LINT-25 accumulated in heterochromatin foci, and LAP2α protein levels were downregulated by proteasomal degradation. Although LAP2α was not required for the upregulation...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2000) 113 (5): 831–839.
Published: 1 March 2000
... that calmodulin may be associated with the mechanism underlying flagellar quiescence induced by 10 −4 M Ca 2+ . ‡ Author for correspondence (e-mail: chikako@biol.s.u-tokyo.ac.jp ) * Present address: Department of Physiology, University of Massachusetts Medical Center, Worcester, MA 01655, USA 10...
Journal Articles
Journal Articles