... aberrant distribution of F-actin in fluorescence cell staining and an increased amount of cytoskeleton-associated actin. Excessive pseudopod formation was also noted in cosA − cells facing chemoattractant gradients. Expressing cosA or its human counterpart mCostars eliminated abnormalities of cosA − cells...

...Peter J. M. Van Haastert Chemotaxis is one of the most fascinating processes in cell biology. Shallow gradients of chemoattractant direct the movement of cells, and an intricate network of signalling pathways somehow instructs the movement apparatus to induce pseudopods in the direction...

...-u.ac.jp ) 22 1 2008 © The Company of Biologists Limited 2008 2008 Amoeboid movement Cell migration Pseudopod Cell migration plays an essential role during the development of most organisms (reviewed in Lauffenburger and Horwitz, 1996 ; Ridley et al., 2003 ; Raftopoupou...

... Crac -GFP at the leading edge in a cAMP gradient. We show that cAMP determines the probability of patch formation (half-maximal effect at 0.5 nM cAMP) but not the size, lifetime or intensity of patches, indicating that patches are self-organizing structures. A pseudopod is extended from the area...

... of the cell and formation of a predominant pseudopod. As p21-activated kinases PAKs are known to regulate eukaryotic cell motility and morphology, we investigated the role of PAK in E. histolytica. We showed that the C-terminal domain of EhPAK comprised a constitutive kinase activity in vitro...

... . * Author for correspondence (e-mail: [email protected] ) 27 9 2002 © The Company of Biologists Limited 2003 2003 Traction force Pseudopod Amoeboid movement Silicone substrate Myosin II, conventional myosin, is believed to play a crucial role in cell movement...

... without quinine treatment, and in protrusion elongation in general. Movies available on-line Author for correspondence (e-mail: [email protected] ) 3 3 2001 © The Company of Biologists Limited 2001 2001 Pseudopod Myosin Actin polymerization Contraction...

... with profilin and spread throughout the cytoplasm. * Author for correspondence (e-mail: [email protected] ) 04 08 1999 18 10 1999 © 1999 by Company of Biologists 1999 Antibody Cell motility Endocytosis Pseudopod The small protein, profilin, is essential in yeast...

...Ivan R. Nabi ABSTRACT Polarization of the motile cell is associated with the formation of a distinct plasma membrane domain, the pseudopod, whose stabilization determines the directionality of cell movement. The rapid movement of cells over a substrate requires that an essential aspect of cell...

...Hiromi Sesaki; Satoshi Ogihara ABSTRACT Exocytosis has been proposed to participate in the formation of pseudopods. Using video-enhanced microscopy, we directly visualized exocytosis of single vesicles in living Physarum plasmodia migrating on a substrate. Vesicles containing slime, the plasmodial...

... motility and ion transport are regulated by separate G protein-coupled pathways. * Author for correspondence 21 06 1993 19 10 1993 © 1994 by Company of Biologists 1994 G protein K + channel pseudopod bone resorption motility GTP-binding proteins (G proteins...