.... 77 , 97 - 141 . 10.1016/bs.ctm.2015.10.003 Greaves , J. and Chamberlain , L. H. ( 2007 ). Palmitoylation-dependent protein sorting . J. Cell Biol. 176 , 249 - 254 . 10.1083/jcb.200610151 Greaves , J. and Chamberlain , L. H. ( 2011 ). DHHC palmitoyl...

... Transporters Monocarboxylic acids Endocytosis Arrestin Cytosolic termini Protein sorting Protein turnover Substrate specificity Ubiquitylation Fundação para a Ciência e a Tecnologia http://dx.doi.org/10.13039/501100001871 UIDB/04050/2020 PD/BD/135208/2017 SFRH/BD/86221/2012 PTDC/BIA-MIC...

... receptor kinase B (TrkB) ( Vaegter et al., 2011 ), EGF receptor ( Al-Akhrass et al., 2017 ), sphingomyelin phosphodiesterase ( Ni and Morales, 2006 ) and vacuolar protein sorting-associated protein 26B ( Kim et al., 2010 ) ( Fig. 1 B; Table S1 ). These findings corroborated our strategy for identifying...

...-gated sodium channel β2 subunit associates with cholesterol-rich lipid rafts by means of S-palmitoylation, which may contribute to establishing its polarized cell surface localization. Protein sorting Palmitoylation Voltage-gated sodium channel SCN2B Na V 1.5 Cardiac arrhythmia...

... machinery can, in principle, process mitochondrial proteins but, under normal conditions, active mitochondrial targeting pathways dominate the kinetic competition against GET recognition. ER GET Mitochondria Outer membrane Protein sorting Tail-anchor Deutsche Forschungsgemeinschaft...

...Nicole Heucken; Rumen Ivanov; Jenny Russinova ABSTRACT Protein sorting in the endomembrane system is responsible for the coordination of cellular functions. Plant intracellular trafficking has its own unique features, which include specific regulatory aspects of endosomal sorting and recycling...

... (TMD) dominates discussion about determinants required for protein sorting to the plasma membrane. Transmembrane adaptor proteins (TRAP) are involved in signalling events which take place at the plasma membrane. Members of this protein family have TMDs of varying length. We were interested in whether...

... is regulated by p150 glued to coordinate protein sorting and transport carrier formation with the subsequent long-range transport towards the Golgi complex along microtubules. Fig. 4. Knockdown of p150 glued inhibits cargo concentration at the ERES. (A) Cells were treated with three different siRNAs...

... protein sorting late in the secretory pathway of Saccharomyces cerevisiae.   J. Cell Biol.   137 , 1469 – 1482 . 10.1083/jcb.137.7.1469 Rothman   J. H. , Stevens   T. H. ( 1986 ). Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late...

... and Massachusetts General Hospital, Boston, MA 02129, USA 12 11 2007 © The Company of Biologists Limited 2008 2008 SNARE ENTH domain TGN Endosome Protein sorting The vesicle-mediated membrane transport is a multi-step process, consisting of vesicle formation (budding), targeting...

..., therefore mutation of the WLM motif will abolish interaction with AP-1 as there will be little or no CIMPR in the TGN to interact with AP-1. E-mail: [email protected] 12 5 2007 © The Company of Biologists Limited 2007 2007 Trans-Golgi network Endosomes CIMPR Protein sorting...

... identity of the ERGIC. It will be interesting to determine the changes in free calcium and pH from the ER to the ERGIC. The issue of protein sorting in the ERGIC becomes more complex in the case of cargo proteins that require the assistance of recycling transport receptors during ER export...

... © The Company of Biologists Limited 2005 2005 Trypanosome Glycosylphosphatidylinositol Flagellar pocket Transferrin receptor Protein sorting African trypanosomes are phylogenetically ancient parasitic protozoa that cause human (sleeping sickness) and veterinary (Nagana) disease...

... in polarized sorting in differentiated cells, raft clustering might also play an important role in the biogenesis of apical membrane domains during development. © The Company of Biologists Limited 2004 Protein sorting Epithelial cells Rafts Apical membrane Most cell types generated...

... determine the sorting of Lamp 1 and LAP in endosomes, mediating either the direct or the indirect pathway to lysosomes. *Address for correspondence (e-mail: [email protected] ) 21 9 2001 © The Company of Biologists Limited 2002 2002 Endosome Protein sorting Cytoplasmic tail...

... Allan , B. B. and Balch , W. E. ( 1999 ). Protein sorting by directed maturation of Golgi compartments . Science 285 , 63 – 66 . 10.1126/science.285.5424.63 Bahr , V. , Stierhof Y.-D. , Ilg T. , Demar , M. , Quinten M. and Overath , P. ( 1993...

...: Département des Récepteurs et Protéines Membranaires, Ecole Supérieure de Biotechnologie de Strasbourg, Strasbourg, France 09 05 2000 22 06 2000 © 2000 by Company of Biologists 2000 Membrane traffic MDCK cell Protein sorting Annexin 13 annexins have so far been...

...., 1999a ). However, there are currently no specific candidates for a Golgi-associated α -spectrin. Cytoskeleton Cargo selection Linked mosaic Microdomain Actin Protein sorting Ankyrin ARF SAATS Golgi scaffold A fundamental and striking property of eukaryotic cells...

... Biosynthetic pathway p24 protein family Morphogenesis Protein sorting Recently, a new family of transmembrane proteins has been discovered in animals, fungi and plants (the p24-family: Stamnes et al., 1995 ; Emery et al., 1999 ). Although their precise functions remain unclear or controversial...

... amino acid of HER-2 is valine. * Author for correspondence (e-mail: [email protected] ) 25 02 1999 18 12 1998 © 1999 by Company of Biologists 1999 ProTGF-α MT1-MMP Protein sorting Protein trafficking ER retention The sorting of cell surface...