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Keywords: Protein interaction
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Journal Articles
J Cell Sci (2021) 134 (24): jcs259060.
Published: 15 December 2021
... immune response Protein interaction Vesicle trafficking National Natural Science Foundation of China http://dx.doi.org/10.13039/501100001809 31870730 The innate immune system, the first line of host defense, is critical for a host to combat microbial invasion including by viruses...
Includes: Supplementary data
Journal Articles
In collection:
Cytoskeleton
J Cell Sci (2016) 129 (12): 2438–2447.
Published: 15 June 2016
... to integrate microtubules and actin filaments in certain regions of cells. In astrocytes, this interaction can modulate their migration. Kinesin-12 Kif15 Microtubule Myosin-IIB Protein interaction Rat astrocytes Migration National Natural Science Foundation of China 10.13039/501100001809...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (15): 3390–3400.
Published: 1 August 2013
... ( [email protected] ) 20 05 2013 © 2013. Published by The Company of Biologists Ltd 2013 Protein interaction Cell polarity Yeast Septin assembly Myosin assembly Septin filaments provide a distinct compartment and scaffold for the contractile actin-myosin ring and other...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (12): 2629–2640.
Published: 15 June 2013
... was previously shown to hydroxylate other substrates within a highly conserved protein interaction domain, termed the ankyrin repeat domain (ARD). However, to date, the biological role of FIH-1-dependent ARD hydroxylation could not be clarified for any ARD-containing substrate. The apoptosis-stimulating p53...
Journal Articles
Journal Articles
J Cell Sci (2012) 125 (24): 6058–6070.
Published: 15 December 2012
... with the proteins of the IKK-complex in situ , we employed proximity ligation assays (PLA). These assays combine antibody-labelling with signal detection by rolling-circle amplification of secondary antibody-linked oligonucleotides and subsequent fluorescent staining, thus indicating protein interactions...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (18): 4230–4240.
Published: 15 September 2012
... translocation Protein interaction Subcellular trafficking TMD0 Lysosomes are single-membrane-bound organelles for degradation of endogenous or exogenous macromolecules. Therefore, lysosomes are filled with an armada of different hydrolases that function optimally at acidic pH. Mutations...
Includes: Supplementary data
Journal Articles
In collection:
Proteostasis
J Cell Sci (2012) 125 (17): 4103–4113.
Published: 1 September 2012
... ) 19 4 2012 © 2012. Published by The Company of Biologists Ltd 2012 Constraint interaction networks Cytokinesis Protein interaction Split–Ubiquitin Systems biology To separate mother from daughter, yeast cells undergo a well-orchestrated set of biochemical reactions...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (19): 3235–3246.
Published: 1 October 2011
... the carboxyl-terminal tail domain of BMP type II receptor . Mol. Cell. Biol. 27 , 5776 - 5789 . Chen Y. G. , Wang Z. , Ma J. , Zhang L. , Lu Z. ( 2007 ). Endofin, a FYVE domain protein, interacts with Smad4 and facilitates transforming growth factor-beta signaling . J...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (11): 1917–1926.
Published: 1 June 2009
... in neurodegeneration, suggesting a novel therapeutic target in neurodegenerative diseases. * Author for correspondence (e-mail: [email protected] ) 23 2 2009 © The Company of Biologists Limited 2009 2009 HtrA2 (Omi) Heat-shock protein Oligomeric amyloid-β protein Protein interaction...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (4): 487–495.
Published: 15 February 2008
..., differentiation and inflammatory processes, as a protein interaction partner of NOD2. We demonstrate a complex influence of the CD147-NOD2 interaction on NOD2-dependent signaling responses. We show that CD147 itself acts as an enhancer of the invasion of Listeria monocytogenes , an intracellular bacterial...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (2): 265–275.
Published: 15 January 2007
... is redirected from the nucleoplasm to the nucleoli. Thus, we propose that the NoLS may be used as a tool to visualize and prove protein interactions in a cellular context. References Adachi, Y., Copeland, T. D., Hatanaka, M. and Oroszlan, S. ( 1993 ). Nucleolar targeting signal of Rex protein of human T...
Journal Articles
J Cell Sci (2006) 119 (11): 2386–2397.
Published: 1 June 2006
... and controlling it are not known. Recently, presynaptic ryanodine-sensitive Ca 2+ stores have been implicated in spontaneous, as well as depolarisation-induced, exocytosis in the central and peripheral nervous system. Ryanodine receptor Snapin SNARE complex Protein interaction Neurosecretion ©...
Journal Articles
In collection:
Proteostasis
J Cell Sci (2005) 118 (4): 723–732.
Published: 15 February 2005
... for correspondence (e-mail: [email protected] ) 24 11 2004 © The Company of Biologists Limited 2005 2005 Sec complex Split-ubiquitin Signal sequence Protein interaction Saccharomyces cerevisiae Protein translocation across the membrane of the endoplasmic reticulum (ER...
Journal Articles
J Cell Sci (2004) 117 (2): 233–242.
Published: 15 January 2004
... proteins, is integrated into basement membranes via specific protein interactions. We employed a fusion peptide approach as a first step towards examining how usherin is integrated into the basement membrane suprastructure. Fig. 2 illustrates the domain structure of the usherin protein, and indicates...
Journal Articles
In collection:
Proteostasis
J Cell Sci (2003) 116 (17): 3623–3634.
Published: 1 September 2003
... in the living cells of the yeast Saccharomyces cerevisiae . We found that Pex10p plays a central role in the protein interaction network by connecting the ubiquitin conjugation enzyme Pex4p to the other members of the protein import machinery. A yeast strain harboring a deletion of PEX3 enabled us to estimate...
Journal Articles
J Cell Sci (2003) 116 (10): 1949–1957.
Published: 15 May 2003
... as multifunctional protein-protein interaction modules that play a central role in organizing diverse cell signaling assemblies ( Fujita and Kurachi, 2000 ; Harris and Lim, 2001 ). To our knowledge, none of SAP97 partners already described has been shown to interact with its PDZ3 domain. The neuronal G-protein...
Journal Articles
In collection:
Proteostasis
J Cell Sci (2001) 114 (24): 4629–4635.
Published: 15 December 2001
... for its Rer1p-dependent ER localization. In order to elucidate the mechanism of Rer1p involvement in ER localization of Mns1p, we applied the split-ubiquitin system to determine whether these proteins interact. Using this method, we demonstrate that both Mns1p and Sec12p interact with Rer1p in vivo...
Journal Articles
J Cell Sci (2001) 114 (1): 59–68.
Published: 1 January 2001
... primarily to reduce its availability. * Author for correspondence (e-mail: [email protected] ) © 2001 by Company of Biologists 2001 Nuclear structure Nuclear protein Protein interaction Supramolecular regulation PML Sp100 Nuclear bodies described by Bernhard’s group ( de...
Journal Articles
J Cell Sci (1994) 107 (1): 329–338.
Published: 1 January 1994
... 09 1993 14 10 1993 © 1994 by Company of Biologists 1994 basement membrane protein interaction integrin nidogen fibulin-1 Laminin and collagen IV are the major constituents of basement membranes, where they exist as multiple isoforms with different distributions...