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Keywords: Prostate cancer
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Journal Articles
J Cell Sci (2021) 134 (14): jcs258332.
Published: 28 July 2021
...Fatma Özgün; Zeynep Kaya; Tunç Morova; Bart Geverts; Tsion E. Abraham; Adriaan B. Houtsmuller; Martin E. van Royen; Nathan A. Lack ABSTRACT Androgen receptor (AR) splice variants are proposed to be a potential driver of lethal castration-resistant prostate cancer. AR splice variant 7 (ARv7...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (24): 4629–4641.
Published: 15 December 2015
...Robert L. Satcher; Tianhong Pan; Mehmet A. Bilen; Xiaoxia Li; Yu-Chen Lee; Angelica Ortiz; Andrew P. Kowalczyk; Li-Yuan Yu-Lee; Sue-Hwa Lin ABSTRACT Cadherin-11 (Cad11) cell adhesion molecule plays a role in prostate cancer cell migration. Because disassembly of adhesion complexes through...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (10): 2161–2173.
Published: 15 May 2014
.... , Chuang   A-Y. , Epstein   J. I. , Berman   D. M. ( 2007 ). Roles for the stem cell associated intermediate filament Nestin in prostate cancer migration and metastasis.   Cancer Res.   67 , 9199 – 9206 . 10.1158/0008--5472.CAN--07--0806 Krupkova   O.   Jr , Loja   T. , Zambo   I...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (20): 4800–4811.
Published: 15 October 2012
...Zhipeng Zou; Fangyin Zeng; Wanfu Xu; Chunxia Wang; Zhiyong Ke; Q. Jane Wang; Fan Deng Summary Although protein kinase D3 (PKD3) has been shown to contribute to prostate cancer cell growth and survival, the role of PKD in prostate cancer cell motility remains unclear. Here, we show that PKD2...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (5): 1204–1216.
Published: 01 March 2012
... ( Fig. 1D , bottom panel). These findings show that Aurora A and LIMK2 not only colocalize, but Aurora A also regulates LIMK2 subcellular localization. © 2012. 2012 Chemical genetic Aurora A kinase LIMK2 Breast cancer Prostate cancer Aurora A, a serine/threonine kinase...
Journal Articles
J Cell Sci (2010) 123 (10): 1663–1673.
Published: 15 May 2010
... adhesions. We now report that DU145 human prostate cancer cells with reduced levels of PAK4 expression are unable to successfully migrate in response to HGF, have prominent actin stress fibres, and an increase in the size and number of focal adhesions. Moreover, these cells have a concomitant reduction...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (7): 957–968.
Published: 01 April 2008
... that pathological mutations within the NLS of AR that are associated with prostate cancer and androgen-insensitivity syndrome reduce the binding affinity to importin-α and, subsequently, retard nuclear import; surprisingly, however, the transcriptional activity of these mutants varies widely. Thus, in addition...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (18): 4187–4198.
Published: 15 September 2005
...Pascal Farla; Remko Hersmus; Jan Trapman; Adriaan B. Houtsmuller The androgen receptor (AR) is essential for development of the male gender and in the growth of the majority of prostate cancers. Agonists as well as most antagonists induce translocation of the receptor to the nucleus, whereas only...
Journal Articles
J Cell Sci (2004) 117 (18): 4135–4142.
Published: 15 August 2004
... role for the translocon which is involved in the control of the [Ca 2+ ] ER and could therefore supervise many physiological processes, including gene expression and apoptosis. Prostate cancer Translocon Puromycin Calcium leak Endoplasmic reticulum LNCaP cells ‡ Author...
Journal Articles
J Cell Sci (2002) 115 (1): 141–151.
Published: 01 January 2002
... 2002 NF-κB IκBα phosphorylation IKK Prostate cancer The signaling pathways that regulate cell proliferation, survival and transformation are of prime interest in cancer biology. Recently, the Rel/NF-κB transcription factors, the known regulators of immune and inflammatory responses...