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Keywords: Prolactin
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Journal Articles
J Cell Sci (2011) 124 (20): 3484–3491.
Published: 15 October 2011
... and its regulation. The gland, an essential component of the endocrine system, secretes the hormones prolactin (PRL), growth hormone, thyrotrophin, gonadotrophins and adrenocorticotrophin, which are generated from specific differentiated cells located within the anterior lobe of the pituitary...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (21): 3683–3692.
Published: 1 November 2010
... prolactin or growth hormone. We found that DG regulates signaling by both hormones in a manner that is dependent on laminin-111 binding, but independent of the DG cytoplasmic domain, suggesting that it acts via a co-receptor mechanism reliant on DG-mediated laminin assembly. These results demonstrate...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (3): 424–430.
Published: 1 February 2010
... lactotrophic cells or intact pituitary tissue from bacterial artificial chromosome (BAC) transgenic rats in which a large prolactin genomic fragment directed expression of luciferase or destabilised enhanced green fluorescent protein (d2EGFP). Prolactin promoter activity in transgenic pituitaries varied...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (19): 4101–4116.
Published: 1 October 2006
.... Designed after the prolactin promoter-enhancer, it allows for the direct visualization of estrogen receptor α (ERα) and/or Pit-1 interactions at a physiologically regulated transcription locus. ERα- and ligand-dependent cofactor recruitment, large-scale chromatin modifications and transcriptional activity...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (15): 3277–3288.
Published: 1 August 2005
... expression in each cell. The data are shown as the means of each cell population with error bars denoting s.e.m. * Author for correspondence (e-mail: rnd2v@virginia.edu ) 21 4 2005 © The Company of Biologists Limited 2005 2005 Transcriptional regulation Prolactin Nuclear co...
Journal Articles
J Cell Sci (2004) 117 (11): 2193–2202.
Published: 1 May 2004
... rat pituitary lactotrophs. Secretory stimulation with high external [K + ] resulted in 100 exocytic sites per cell that were labeled by extracellular antibodies against the peptide hormone prolactin. Morphological analysis demonstrated that the prolactin was retained and internalized in intact dense...
Journal Articles
J Cell Sci (2004) 117 (2): 271–280.
Published: 15 January 2004
... laminin co-operates with soluble factors such as prolactin to regulate tissue-specific gene expression. The mechanism of matrix and prolactin crosstalk and the activation of downstream signals are not fully understood. Because integrins organize the cytoskeleton, we analysed the contribution...
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (1991) 99 (1): 79–89.
Published: 1 May 1991
... for correspondence 30 10 1990 19 02 1991 © 1991 by Company of Biologists 1991 microtubules cytokeratin actin pituitary cells secretion prolactin The hypothalamic tripeptide, thyroliberin (TRH), exerts a well-known stimulatory effect on prolactin (PRL) secretion. This effect has...