... unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Aggresomes BAG6 Mislocalised membrane proteins Polyubiquitylation Protein degradation Small glutamine-rich tetratricopeptide repeat-containing protein alpha Hydrophobic amino...

... and overexpressed H-Ras protein is controlled by β-TrCP-mediated ubiquitylation, proteasomal degradation and the Wnt/β-catenin signaling pathway. The interaction of H-Ras with the WD40 domain of β-TrCP targeted H-Ras for polyubiquitylation and degradation. This process was stimulated by Axin or adenomatous...