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Keywords: Poly(ADP-ribose) polymerase
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Journal Articles

Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling

Godelieve Smeenk, Wouter W. Wiegant, Jurgen A. Marteijn, Martijn S. Luijsterburg, Nicholas Sroczynski, Thomas Costelloe, Ron J. Romeijn, Albert Pastink, Niels Mailand, Wim Vermeulen, Haico van Attikum
Journal: Journal of Cell Science
J Cell Sci (2013) 126 (4): 889–903.
https://doi.org/10.1242/jcs.109413
Published: 15 February 2013
... complexes, is recruited to DSBs in a poly(ADP-ribose) polymerase 1 (PARP1)-dependent manner. Remarkably, PARP activity, although dispensable for the efficient spreading of γH2AX into damaged chromatin, selectively promotes spreading of SMARCA5, the E3 ubiquitin ligase RNF168, ubiquitin conjugates...
View article titled, Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling
Open the PDF for Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling in another window
Includes: Supplementary data
Journal Articles

Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of poly(ADP-ribose) polymerase expression

Stefan Goebel, Uwe Gross, Carsten G. K. Lüder
Journal: Journal of Cell Science
J Cell Sci (2001) 114 (19): 3495–3505.
https://doi.org/10.1242/jcs.114.19.3495
Published: 1 October 2001
... molecule protein kinase Cδ. In parallel, poly(ADP-ribose) polymerase protein levels were prominently downregulated by T. gondii , irrespective of whether HL-60 and U937 cells had been treated with pro-apototic stimuli or left untreated. However, poly(ADP-ribose) polymerase mRNA levels remained unchanged...
View article titled, Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of <span class="search-highlight">poly</span>(<span class="search-highlight">ADP</span>-<span class="search-highlight">ribose</span>) <span class="search-highlight">polymerase</span> expression
Open the PDF for Inhibition of host cell apoptosis by Toxoplasma gondii is accompanied by reduced activation of the caspase cascade and alterations of <span class="search-highlight">poly</span>(<span class="search-highlight">ADP</span>-<span class="search-highlight">ribose</span>) <span class="search-highlight">polymerase</span> expression in another window
Journal Articles

DNA-binding activity of the N-terminal cleavage product of poly(ADP-ribose) polymerase is required for UV mediated apoptosis

Jin Woo Kim, Jungyeon Won, Seonghyang Sohn, Cheol O. Joe
Journal: Journal of Cell Science
J Cell Sci (2000) 113 (6): 955–961.
https://doi.org/10.1242/jcs.113.6.955
Published: 15 March 2000
...Jin Woo Kim; Jungyeon Won; Seonghyang Sohn; Cheol O. Joe ABSTRACT The role of the N-terminal cleavage product of poly(ADP-ribose) polymerase (PARP) on UV mediated apoptosis was investigated in cultured HeLa cells. Ultrastructural analysis of cells expressing caspase-resistant PARP (PARP D214A...
View article titled, DNA-binding activity of the N-terminal cleavage product of <span class="search-highlight">poly</span>(<span class="search-highlight">ADP</span>-<span class="search-highlight">ribose</span>) <span class="search-highlight">polymerase</span> is required for UV mediated apoptosis
Open the PDF for DNA-binding activity of the N-terminal cleavage product of <span class="search-highlight">poly</span>(<span class="search-highlight">ADP</span>-<span class="search-highlight">ribose</span>) <span class="search-highlight">polymerase</span> is required for UV mediated apoptosis in another window