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Keywords: Polo
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Journal Articles
J Cell Sci (2020) 133 (13): jcs244442.
Published: 01 July 2020
...Cedric Landmann; Priscillia Pierre-Elies; Damien Goutte-Gattat; Emilie Montembault; Marie-Charlotte Claverie; Anne Royou ABSTRACT The DNA damage sensor Mre11-Rad50-Nbs1 complex and Polo kinase are recruited to DNA lesions during mitosis. However, their mechanism of recruitment is elusive. Here...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (3): 576–583.
Published: 01 February 2012
... chromosomes that favors amphitelic orientation but the regulation of this process and molecular components are unknown. Abnormal chromosome–spindle interactions do occur but are corrected through the activity of Aurora B, which destabilizes erroneous attachments. Here, we address the role of Drosophila POLO...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2011) 124 (20): 3441–3449.
Published: 15 October 2011
... division. We find that this block to cell division relies upon TOR and MAPK signalling and that mitotic entry during recovery from this block is regulated by the Aurora kinase Ark1. We show that Ark1 phosphorylation of polo kinase Plo1 within the linker region between the kinase domain and polo boxes...
Includes: Supplementary data
Journal Articles
J Cell Sci (2003) 116 (12): 2453–2460.
Published: 15 June 2003
... results from yeast and vertebrates, we show here that the effects of stabilized securin with mutations in the D-box are enhanced in vivo by reduced Polo kinase function or by mitotically stabilized Cyclin A. However, we also show that PIM contains a KEN-box, which is required for mitotic degradation in...
Journal Articles
J Cell Sci (2003) 116 (7): 1377–1387.
Published: 01 April 2003
...Nicola Reynolds; Hiroyuki Ohkura Polo kinases play multiple roles in cell cycle regulation in eukaryotic cells. In addition to the kinase domain, conservation at the primary sequence level is also found in the non-catalytic region mainly in three blocks, namely the polo boxes. Although several...