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Keywords: Plakophilin
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Journal Articles
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Adhesion , Imaging
J Cell Sci (2021) 134 (21): jcs258906.
Published: 10 November 2021
... and mechanically integrate cells across tissues, dissipating mechanical stress. They comprise five major protein classes – desmocollins and desmogleins (the desmosomal cadherins), plakoglobin, plakophilins and desmoplakin – whose individual contribution to the structure and turnover of desmosomes is poorly...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (10): jcs212191.
Published: 22 May 2018
... signaling regulates the phosphorylation-dependent association of plakophilins 1 and 3 (PKP1 and PKP3) with 14-3-3 protein isoforms, and uncover unique and partially antagonistic functions of members of the 14-3-3 family in the regulation of desmosomes. 14-3-3γ associated primarily with cytoplasmic PKP1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (17): 3782–3793.
Published: 1 September 2014
... with a host of desmosomal plaque proteins, including plakophilins, plakoglobin and desmoplakin, which, in turn, recruit the intermediate filament cytoskeleton to sites of cell–cell contact. Although the individual components of the desmosome are known, mechanisms regulating the assembly of this junction...
Includes: Supplementary data
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J Cell Sci (2006) 119 (5): 797–806.
Published: 1 March 2006
... Cadherin Plakoglobin Plakophilin Pemphigus Keratoderma Cardiomyopathy Desmosomes are intercellular junctions that connect intermediate filaments to the cell surface and mediate strong cell-cell adhesion. They are particularly prominent in stratified squamous epithelia and the myocardium...
Journal Articles
J Cell Sci (2003) 116 (7): 1219–1233.
Published: 1 April 2003
...Mechthild Hatzfeld; Kathleen J. Green; Helmut Sauter p0071, a member of the armadillo protein family, is most closely related to p120 ctn and the plakophilins 1-3. Whereas plakophilins are desmosomal plaque proteins, p120 ctn localizes to adherens junctions and interacts with classical cadherins...
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Journal Articles
Journal Articles
J Cell Sci (2000) 113 (8): 1319–1334.
Published: 15 April 2000
...-catenin/NPRAP/neurojungin p0071 Plakophilin Cadherin Clustering RhoA Kaiso Presenilin Armadillo/β-catenin p120 (p120 ctn , hereafter p120) was originally identified as a prominent substrate of the Src oncoprotein ( Reynolds et al., 1989 ). cDNA cloning revealed that it contains...
Journal Articles
J Cell Sci (1999) 112 (14): 2265–2276.
Published: 15 July 1999
...Stefan Bonné; Jolanda van Hengel; Friedel Nollet; Patrick Kools; Frans van Roy ABSTRACT We report on a novel Armadillo-like protein, termed plakophilin-3. The human protein, which is encoded by a 2.8 kb messenger RNA, has a predicted molecular mass of 87 kDa. The protein comprises 10 Armadillo-like...