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Keywords: Plakoglobin
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Journal Articles
J Cell Sci (2014) 127 (10): 2174–2188.
Published: 15 May 2014
...-Seetharam; Sorab N. Dalal ABSTRACT The regulation of cell–cell adhesion is important for the processes of tissue formation and morphogenesis. Here, we report that loss of 14-3-3γ leads to a decrease in cell–cell adhesion and a defect in the transport of plakoglobin and other desmosomal proteins to the cell...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (14): 3031–3042.
Published: 15 July 2013
...Zackie Aktary; Stephen Kulak; John Mackey; Nadia Jahroudi; Manijeh Pasdar Summary Plakoglobin (γ-catenin), a constituent of the adherens junction and desmosomes, has signaling capabilities typically associated with tumor/metastasis suppression through mechanisms that remain undefined. To determine...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (13): 3202–3209.
Published: 01 July 2012
.... Loss of Rnd3 expression is also associated with resistance to cisplatin-mediated apoptosis in keratinocytes and this resistance is mediated through the desmosomal protein plakoglobin. We propose a novel plakoglobin-dependent role for Rnd3 in the regulation of keratinocyte cell death. Cisplatin...
Journal Articles
J Cell Sci (2006) 119 (5): 797–806.
Published: 01 March 2006
... thus be to relay messages from the outside of the cell to the inside through desmosomal cadherins. Indeed, recent studies have indicated that plakoglobin is required for pemphigus antibodies to disrupt desmosomal adhesion fully in cultured keratinocytes ( Caldelari et al., 2001 ). Interestingly, even...
Journal Articles
J Cell Sci (2003) 116 (7): 1219–1233.
Published: 01 April 2003
...-desmosomal cadherins. Head and armadillo repeat domains both interacted with plakoglobin by binding to different sites. Our data suggest that, in addition to plakoglobin, p0071 is the second armadillo protein present in both types of adhesive junctions and may play a role in regulating crosstalk between...
Journal Articles
J Cell Sci (2002) 115 (23): 4587–4595.
Published: 01 December 2002
... expression occur independently of β-catenin and correlate with repression of transcription from Tcf/Lef-responsive promoters. Moreover, during differentiation,β-catenin-null cells assemble normal intercellular adhesion junctions owing to the substitution of β-catenin with plakoglobin, whereas the expression...