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Keywords: Physiological ER stress
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Journal Articles
The requirement of IRE1 and XBP1 in resolving physiological stress during Drosophila development
Open Access
Journal:
Journal of Cell Science
J Cell Sci (2017) 130 (18): 3040–3049.
Published: 15 September 2017
... activities. IRE1 and XBP1 are developmentally essential genes in Drosophila and mammals, but the source of the physiological ER stress and the relative contributions of XBP1 activation versus other IRE1 functions to development remain unknown. Here, we employed Drosophila to address this question. Explicitly...
Includes: Supplementary data