...Che-Hsiung Liu; Murali K. Bollepalli; Samuel V. Long; Sabrina Asteriti; Julie Tan; Julie A. Brill; Roger C. Hardie ABSTRACT Phototransduction in Drosophila is mediated by phospholipase C-dependent hydrolysis of PIP 2­ , and is an important model for phosphoinositide signalling. Although generally...

.... A microarray analysis has previously been used to compare the genes expressed in wild-type heads with heads from a mutant fly that lacked eyes in order to identify eye-enriched genes, which led to the further identification of some genes functioning in phototransduction ( Xu et al., 2004 ). However, owing...

...Roger C. Hardie; Che-Hsiung Liu; Alexander S. Randall; Sukanya Sengupta ABSTRACT In order to monitor phosphoinositide turnover during phospholipase C (PLC)-mediated Drosophila phototransduction, fluorescently tagged lipid probes were expressed in photoreceptors and imaged both in dissociated cells...

...Robert S. Molday; Orson L. Moritz ABSTRACT Retinal photoreceptor cells contain a specialized outer segment (OS) compartment that functions in the capture of light and its conversion into electrical signals in a process known as phototransduction. In rods, photoisomerization of 11- cis to all- trans...

... TRP and TRPL predominantly specify the assembly of homomeric TRP and TRPL channels. Drosophila Channel assembly Phototransduction TRP ion channel Vision Chimeric channels * These authors contributed equally to this work ‡ Author for correspondence ( Armin.Huber@uni...

... in phototransduction. Cell 54 , 723 -733. Brann, M. R. and Cohen, L. V. ( 1987 ). Diurnal expression of transducin mRNA and translocation of transducin in rods of rat retina. Science 235 , 585 -587. Broekhuyse, R. M., Tolhuizen, E. F., Janssen, A. P. and Winkens, H. J. ( 1985 ). Light induced shift...

...N. E. Meyer; T. Joel-Almagor; S. Frechter; B. Minke; A. Huber Signal-mediated translocation of transient receptor potential (TRP) channels is a novel mechanism to fine tune a variety of signaling pathways including neuronal path finding and Drosophila photoreception. In Drosophila phototransduction...