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Keywords: Phospholipase D
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Journal Articles
In collection:
Lipid biology
J Cell Sci (2014) 127 (14): 3104–3115.
Published: 15 July 2014
... stimulates lipid droplet formation by activating the long-chain fatty acid receptor FFAR4, which signals through a pertussis-toxin-sensitive G-protein signalling pathway involving phosphoinositide 3-kinase (PI3-kinase), AKT (also known as protein kinase B) and phospholipase D (PLD) activities. This initial...
Journal Articles
J Cell Sci (2012) 125 (12): 3004–3011.
Published: 15 June 2012
... of phosphatidylinositol phosphates, which in turn activate the phospholipase D, Spo14; (2) is required for a late step in cytokinesis that gives rise to spores; and (3) regulates a membrane-bending activity that generates intralumenal vesicles. These results demonstrate that Vps13 plays a broader role in membrane biology...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (12): 1973–1983.
Published: 15 June 2011
... by phospholipase D (PLD) enzymes. Neutrophils, important cells of the innate immune system, maintain the body's defence against infection. Previous studies have implicated PLD-generated PA in neutrophil function; these have relied heavily on the use of primary alcohols to act as inhibitors of PA production...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2006) 119 (8): 1645–1654.
Published: 15 April 2006
...Abigail R. Mazie; Julie K. Spix; Ethan R. Block; Hewa B. Achebe; Jes K. Klarlund Phospholipase D catalyzes the hydrolysis of phosphatidylcholine to generate phosphatidic acid, and there is currently much interest in elucidating messenger functions for this molecule. We report here that wounding...
Journal Articles
Journal Articles
J Cell Sci (2004) 117 (19): 4365–4375.
Published: 1 September 2004
... Phospholipase D Rab11 is a small GTPase that plays a role in regulating membrane traffic from the endocytic recycling compartment (ERC) to either the plasma membrane or the trans-Golgi network (TGN). Recently, several Rab11-interacting proteins have been identified that share a highly homologous Rab11...
Journal Articles