...) could be phagocytosed by DCs, regardless of whether they had previously been experimentally opsonized with either the complement C3 component or specific antibodies. Parasites could survive and even multiply in these cells for at least 72 hours, within parasitophorous vacuoles displaying phagolysosomal...

...Audra J. Charron; L. David Sibley Successful replication of the intracellular parasite Toxoplasma gondii within its parasitophorous vacuole necessitates a substantial increase in membrane mass. The possible diversion and metabolism of host cell lipids and lipid precursors by Toxoplasma...

... forms can be internalized by these host cells at different stages of the infectious process and eventually establish themselves within parasitophorous vacuoles exhibiting phagolysosomal properties. To determine whether the biogenesis of these organelles differs according to the parasitic stage used...

...Jean-Claude Antoine; Thierry Lang; Eric Prina; Nathalie Courret; Raymond Hellio ABSTRACT In their amastigote stage, Leishmania are obligatory intracellular parasites of mammalian macrophages, residing and multiplying within phagolysosomal compartments called parasitophorous vacuoles (PV...

...Ulrich E. Schaible; Paul H. Schlesinger; Thomas H. Steinberg; Walter F. Mangel; Toshihide Kobayashi; David G. Russell ABSTRACT The intracellular parasite Leishmania survives and proliferates in host macrophages. In this study we show that parasitophorous vacuoles of L. mexicana gain access...

... capacities of the host cells they invade. 14 03 1998 © 1998 by Company of Biologists 1998 Host cell invasion Membrane biogenesis Parasitophorous vacuole Plasmodium Toxoplasma Apicomplexa are unicellular eukaryotes which are obligatory intracellular parasites with short...

...Thierry Lang; Raymond Hellio; Paul M. Kaye; Jean-Claude Antoine ABSTRACT Leishmania donovani amastigotes, the etiological agents of visceral leishmaniasis, are obligate intracellular parasites residing in membrane-bound compartments of macrophages called parasitophorous vacuoles (PV). The study...

... of nutrients, and avoid the macrophage’s antigen-presenting capabilities. All these requirements are dependent on the properties of the parasitophorous vacuole in which Leishmania resides. This study shows that the vacuole possesses membrane proteins characteristic of a lysosome, and has MHC class II molecules...

...A. R. Dluzewski; G. H. Mitchell; P. R. Fryer; S. Griffiths; R. J. M. Wilson; W. B. Gratzer ABSTRACT We have attempted to determine whether the parasitophorous vacuole membrane, in which the malaria parasite (merozoite) encapsulates itself when it enters a red blood cell, is derived from the host...