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Keywords: Pancreatic islets
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Journal Articles
In collection:
J Cell Sci (2016) 129 (14): 2865–2875.
Published: 15 July 2016
...Ge Li; Binlin Wu; Meliza G. Ward; Angie C. N. Chong; Sushmita Mukherjee; Shuibing Chen; Mingming Hao ABSTRACT Pancreatic islet dysfunction leading to insufficient glucose-stimulated insulin secretion triggers the clinical onset of diabetes. How islet dysfunction develops is not well understood...
Includes: Supplementary data
Journal Articles
J Cell Sci (2003) 116 (8): 1463–1469.
Published: 15 April 2003
... the contribution of IB1/JIP-1 to β-cell survival. Exposure of the insulin-producing cell line INS-1 or isolated rat pancreatic islets to cytokines (interferon-γ, tumor necrosis factor-α and interleukin-1β) induced a marked reduction of IB1/JIP-1 content and a concomitant increase in JNK activity and apoptosis rate...