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Keywords: Pancreatic cancer
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Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2017) 130 (6): 1078–1093.
Published: 15 March 2017
...Jing Wang; Kumar Nikhil; Keith Viccaro; Lei Chang; Max Jacobsen; George Sandusky; Kavita Shah ABSTRACT We uncovered a crucial role for the Aurora kinase A (AURKA)–Twist1 axis in promoting epithelial-to-mesenchymal transition (EMT) and chemoresistance in pancreatic cancer. Twist1 is the first EMT...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2013) 126 (15): 3380–3389.
Published: 1 August 2013
...Johannes Fredebohm; Jonas Wolf; Jörg D. Hoheisel; Michael Boettcher Summary Chemotherapy of advanced pancreatic cancer has mainly been gemcitabine-based for the past 15 years, with only limited effect. Recently, combination therapy that also targets checkpoint kinase 1 (CHK1) has become...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2010) 123 (10): 1684–1692.
Published: 15 May 2010
... that BMP-9 promotes the proliferation of these cells via ALK-1. Furthermore, in vivo angiogenesis was promoted by BMP-9 in a Matrigel plug assay and in a BxPC3 xenograft model of human pancreatic cancer. Consistent with these in vivo findings, BMP-9 enhanced the proliferation of in-vitro-cultured normal...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (20): 4901–4912.
Published: 15 October 2005
.... and Malfertheiner, P. ( 2002 ). Reduced PTEN expression in the pancreas overexpressing transforming growth factor-beta 1. Br. J. Cancer 86 , 257 -262. Ellenrieder, V., Hendler, S., Ruhland, S., Boeck, W., Adler, G. and Gress, T. M. ( 2001a ). TGF-β-induced invasiveness of pancreatic cancer cells...
Journal Articles