.... Here, we characterize angiomotin (AMOT) isoform 2 (p80, referred to as Ap80) as a novel KIF13B interactor that promotes binding of another MAGUK, the polarity protein and Crumbs complex component PALS1, to KIF13B. Live-cell imaging analysis indicated that Ap80 is concentrated at and recruits PALS1...

... (Sdt)/protein associated with Lin7 subfamily member-1 (Pals1)/Mpp5 family of MAGUK proteins ( Tepass and Knust, 1993 ; Kamberov et al., 2000 ; Hong et al., 2001 ; Bachmann et al., 2001 ). In addition to PDZ, SH3, 4.1 and GUK domains, Nok contains the evolutionarily conserved region 1 (ECR1) domain...

... cloned a novel mammalian epithelial Crumbs isoform, Crumbs3 (CRB3). CRB3 exists in a complex at tight junctions(TJs) with Pals1 and PATJ, the mammalian homologues of Stardust and Discs lost, respectively. Here, we observe that overexpression of CRB3 leads to delayed TJ formation in MDCK epithelial cell...