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Keywords: PKD
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Journal Articles

Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation

In collection:
Adhesion
Robert Sroka, Johan Van Lint, Sarah-Fee Katz, Marlon R. Schneider, Alexander Kleger, Stephan Paschke, Thomas Seufferlein, Tim Eiseler
Journal: Journal of Cell Science
J Cell Sci (2016) 129 (12): 2416–2429.
https://doi.org/10.1242/jcs.184721
Published: 15 June 2016
... by protein kinase D1 at S298 modulate E-cadherin adhesion complex composition and F-actin linkage during ligation and dissolution of adherence junctions. Cortactin Adherens junction Vinculin Protein kinase D PKD Cadherin-1 CDH1 Epithelial cadherin E-cadherin Epithelial cells are tightly...
View article titled, Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation
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Includes: Supplementary data
Journal Articles

Mitotic Golgi translocation of ERK1c is mediated by a PI4KIIIβ–14-3-3γ shuttling complex

Inbal Wortzel, Tamar Hanoch, Ziv Porat, Angelika Hausser, Rony Seger
Journal: Journal of Cell Science
J Cell Sci (2015) 128 (22): 4083–4095.
https://doi.org/10.1242/jcs.170910
Published: 15 November 2015
... of phosphorylated ERK1c to a complex that consists of PI4KIIIβ (also known as PI4KB) and the 14-3-3γ dimer (encoded by YWHAB ). The stability of the complex is regulated by protein kinase D (PKD)-mediated phosphorylation of PI4KIIIβ. The complex assembly induces the Golgi shuttling of ERK1c, where it is activated...
View article titled, Mitotic Golgi translocation of ERK1c is mediated by a PI4KIIIβ–14-3-3γ shuttling complex
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Includes: Supplementary data
Journal Articles

PKD2 and PKD3 promote prostate cancer cell invasion by modulating NF-κB- and HDAC1-mediated expression and activation of uPA

Zhipeng Zou, Fangyin Zeng, Wanfu Xu, Chunxia Wang, Zhiyong Ke, Q. Jane Wang, Fan Deng
Journal: Journal of Cell Science
J Cell Sci (2012) 125 (20): 4800–4811.
https://doi.org/10.1242/jcs.106542
Published: 15 October 2012
...Zhipeng Zou; Fangyin Zeng; Wanfu Xu; Chunxia Wang; Zhiyong Ke; Q. Jane Wang; Fan Deng Summary Although protein kinase D3 (PKD3) has been shown to contribute to prostate cancer cell growth and survival, the role of PKD in prostate cancer cell motility remains unclear. Here, we show that PKD2...
View article titled, PKD2 and PKD3 promote prostate cancer cell invasion by modulating NF-κB- and HDAC1-mediated expression and activation of uPA
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Includes: Supplementary data
Journal Articles

Mitochondrial diacylglycerol initiates protein-kinase-D1-mediated ROS signaling

Catherine F. Cowell, Heike Döppler, Irene K. Yan, Angelika Hausser, Yoshio Umezawa, Peter Storz
Journal: Journal of Cell Science
J Cell Sci (2009) 122 (7): 919–928.
https://doi.org/10.1242/jcs.041061
Published: 1 April 2009
...-mediated mitochondria-to-nucleus signaling. * Author for correspondence (e-mail: storz.peter@mayo.edu ) 21 11 2008 © The Company of Biologists Limited 2009 2009 Mitochondria DAG oxidative stress ROS PLD PKD Mitochondrial oxidative stress caused by reactive oxygen...
View article titled, Mitochondrial diacylglycerol initiates protein-kinase-D1-mediated ROS signaling
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Includes: Supplementary data