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Keywords: PKCδ
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Journal Articles
J Cell Sci (2021) 134 (3): jcs250217.
Published: 4 February 2021
... demonstrated that the N-terminal region of KRIT1 is crucial for the ability of PKC to regulate KRIT1 nucleocytoplasmic shuttling, and may be a target for PKC-dependent regulatory phosphorylation events. Finally, we found that silencing of PKCα, but not PKCδ, inhibits phorbol 12-myristate 13-acetate (PMA...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2010) 123 (17): 2901–2913.
Published: 1 September 2010
... to deprivation of growth factor. Protein kinase Cδ (PKCδ), a stress-sensitive protein kinase, has been implicated in tumor progression. In this study, we demonstrate that elevated expression of PKCδ in Madin-Darby canine kidney cells induces a scatter response upon serum starvation, a condition that mimics...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (4): 513–523.
Published: 15 February 2009
...Chien-Lin Chen; Hong-Chen Chen Protein kinase C (PKC) δ, a member of the novel PKC subfamily, has been shown to have an important role in cell proliferation, differentiation, apoptosis and cell motility. In this study, we investigated the effect of green fluorescent protein (GFP)-PKCδ and GFP-PKCα...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (1): 136–144.
Published: 1 January 2009
... that was induced by BzATP (but not by phorbol ester). We examined the isoform specificity of this response, and observed translocation of the Ca 2+ -dependent isoforms PKCα and PKCβI, but not the Ca 2+ -independent isoform PKCδ. Thus, activation of P2X7 receptors specifically induces Ca 2+ -dependent translocation...
Includes: Multimedia, Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2007) 120 (7): 1157–1167.
Published: 1 April 2007
...Chien-Lin Chen; Yeun-Ting Hsieh; Hong-Chen Chen Protein kinase Cδ (PKCδ) has been implicated to play a crucial role in cell proliferation, differentiation and apoptosis. In this study, we have investigated the role of PKCδ in cell motility using Madin-Darby canine kidney cells. Overexpression...
Journal Articles
J Cell Sci (2006) 119 (3): 470–481.
Published: 1 February 2006
... of STAT. We have previously described a unique pathway inducing keratinocyte proliferation, which is mediated by insulin stimulation and depends on protein kinase C δ (PKCδ). In this study, we assessed STAT3 activation downstream of this pathway and characterized the role of PKCδ activation in STAT3...
Journal Articles
J Cell Sci (2003) 116 (15): 3221–3226.
Published: 1 August 2003
...(PKC) δ-selective blocker, rottlerin, inhibited PMA-stimulated depolarization, indicating that PKCδ was involved in regulating depolarization associated with eosinophil NADPH oxidase activity. Thus, the membrane depolarization that is associated with NADPH oxidase activation in eosinophils...