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Keywords: PKCα
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Journal Articles
J Cell Sci (2021) 134 (3): jcs250217.
Published: 4 February 2021
... demonstrated that the N-terminal region of KRIT1 is crucial for the ability of PKC to regulate KRIT1 nucleocytoplasmic shuttling, and may be a target for PKC-dependent regulatory phosphorylation events. Finally, we found that silencing of PKCα, but not PKCδ, inhibits phorbol 12-myristate 13-acetate (PMA...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (13): 2191–2196.
Published: 1 July 2009
...) of intestinal epithelial cells and might have an important impact on intestinal tumorigenesis. We demonstrate here that the expression of PKCα in proliferating intestinal epithelial cells is repressed both in vitro and in vivo by the SOX9 transcription factor. This repression does not require DNA binding...
Journal Articles
J Cell Sci (2009) 122 (1): 136–144.
Published: 1 January 2009
... osteoclast-like cells and live-cell confocal imaging was used to localize enhanced green fluorescent protein (EGFP)-tagged PKC. Benzoylbenzoyl-ATP (BzATP; a P2X7 agonist) induced transient translocation of PKCα to the basolateral membrane. UTP or ATP (10 μM), which activate P2 receptors other than P2X7...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2006) 119 (13): 2837–2846.
Published: 1 July 2006
... between syndecan-4, phosphatidylinositol 4,5-bisphosphate and protein kinase C α (PKCα). Syndecan-4 clustering at the cell surface has also been associated with RhoA-dependent signalling, but the relationship between PKCα and RhoA has not been resolved. Here we present evidence that syndecan-4, PKCα...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (15): 3263–3275.
Published: 1 August 2005
... integrin. It involves translocation (i.e. activation) of PKCα from the cytosol to the membrane and/or the Triton X-100-insoluble subcellular fractions, with recruitment into a complex with α V β 3 integrin, growth factor receptor-bound protein (Grb2), focal adhesion kinase (FAK) in CHO cells and proline...
Journal Articles
J Cell Sci (2002) 115 (18): 3587–3599.
Published: 15 September 2002
...Annunziata Mauro; Carmela Ciccarelli; Paola De Cesaris; Arianna Scoglio; Marina Bouché; Mario Molinaro; Angelo Aquino; Bianca Maria Zani We have previously suggested that PKCα has a role in 12-O-Tetradecanoylphorbol-13-acetate (TPA)-mediated growth arrest and myogenic differentiation in human...