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Keywords: PI 3-kinase
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Journal Articles
J Cell Sci (2018) 131 (22): jcs220517.
Published: 16 November 2018
... . 10.1101/gad.1110003 Jackson , S. P. , Schoenwaelder , S. M. , Goncalves , I. , Nesbitt , W. S. , Yap , C. L. , Wright , C. E. , Kenche , V. , Anderson , K. E. , Dopheide , S. M. , Yuan , Y. , et al. ( 2005 ). PI 3-kinase p110beta: a new target...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (20): 4553–4559.
Published: 15 October 2013
... interaction in cells with the active form of Raf-1 and with p110α, the catalytic subunit of PI 3-kinase. Because the majority of phosphorylated K-Ras is located at the plasma membrane, different localization within this membrane according to the phosphorylation status was explored. Density-gradient...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (16): 2763–2773.
Published: 15 August 2007
... ErbB2 and EGFR and abundant PI 3-kinase. Other docking proteins, such as Shc and STAT5, respond differently to receptor activation. Levels of Shc at the membrane increase two- to five-fold with EGF, whereas pre-associated STAT5 becomes strongly phosphorylated. These data suggest that the distinct...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (15): 2683–2693.
Published: 1 August 2007
... of PI 3-kinase-regulated Arf signaling. Trends Biochem. Sci. 25 , 489 -495. Jaffe, A. and Hall, A. ( 2005 ). Rho GTPases: biochemistry and biology. Annu. Rev. Cell Dev. Biol. 21 , 247 -269. Kaech, S., Parmar, H., Roelandse, M., Bornmann, C. and Matus, A. ( 2001 ). Cytoskeletal...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (15): 2672–2682.
Published: 1 August 2007
... requires p38 and activation of NFκB requires IκB kinase-β. Activation of β-catenin, important in Wnt signaling and the cause of most colon cancers, is inhibited by shear stress through a pathway involving laminin-5, α6β4 integrin, phosphoinositide 3-kinase (PI 3-kinase) and Rac1 coupled with changes...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2006) 119 (4): 605–614.
Published: 15 February 2006
...Karine Lindmo; Harald Stenmark Phosphoinositide (PI) 3-kinases control essential cellular functions such as cytoskeletal dynamics, signal transduction and membrane trafficking. FYVE, PX and PH domains mediate the binding of effector proteins to the lipid products of PI 3-kinases. Recent studies...
Journal Articles
Journal Articles
J Cell Sci (2005) 118 (11): 2471–2484.
Published: 1 June 2005
... 1 and ARAP3 (ARF GAP, Rho GAP, ankyrin repeat, PH protein 3) as PtdIns(3,4,5) P 3 binding proteins ( Hammonds-Odie et al., 1996 ; Krugmann et al., 2002 ). PtdIns(3,4,5) P 3 is a ubiquitous lipid second messenger produced by agonist-stimulated phosphoinositide (PI) 3-kinase and plays...
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Lipid Biology
J Cell Sci (2004) 117 (17): 3923–3933.
Published: 1 August 2004
... scheme of the events occurring at the sites of invasion of epithelial cells by a member of the Chlamydiaceae family. Upstream as well as downstream effectors of Rho GTPases are the phosphatidylinositide (PI) 3-kinases, which catalyse D3-phosphorylation of phosphoinositides and are involved...
Journal Articles
J Cell Sci (2004) 117 (2): 155–161.
Published: 15 January 2004
...Keqiang Ye; Solomon H. Snyder Phosphoinositide (PI) 3-kinase enhancer (PIKE) is a brain-specific GTPase that binds to PI 3-kinase and stimulates its lipid kinase activity. It exists in two forms: the first to be identified, PIKE-S, is shorter and exclusively nuclear; by contrast, the longer form...
Journal Articles
J Cell Sci (2004) 117 (2): 257–270.
Published: 15 January 2004
... the extension of cadherin contacts through a phosphoinositide 3-kinase (PI 3-kinase)-Rac1 pathway. Cadherin adhesions were formed by PI 3-kinase-independent, Rac1-dependent co-recruitment of adhesion complexes and actin filaments. The expression and localization of p120 at the plasma membrane, associated...
Includes: Supplementary data
Journal Articles
J Cell Sci (2003) 116 (17): 3471–3478.
Published: 1 September 2003
.... * Author for correspondence (e-mail: rafirtel@ucsd.edu ) © The Company of Biologists Limited 2003 2003 Chemotaxis Dictyostelium PI 3-kinase Fibroblasts Neutrophils Actin Chemotaxis, movement of a cell towards a chemoattractant signal, is a fundamental process involved in a wide...
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Journal Articles
J Cell Sci (2002) 115 (17): 3357–3367.
Published: 1 September 2002
... PLC-gamma1 downstream from PI 3-kinase. Cell Microbiol. 2 , 465 -477. Bierne, H., Gouin, E., Roux, P., Caroni, P., Yin, H. L. and Cossart, P. ( 2001 ). A role for cofilin and LIM kinase in Listeria-induced phagocytosis. J. Cell Biol. 155 , 101 -112. Birchmeier, C. and Gherardi, E...
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Journal Articles
J Cell Sci (1999) 112 (23): 4175–4183.
Published: 1 December 1999
... Phosphoinositide PI 3-kinase Signal transduction Zinc finger Many biochemical processes in the cell occur at the interface between the cytosol and an intracellular membrane. Vesicular trafficking, signal transduction and actin-regulated membrane rearrangements are examples of processes that require...
Journal Articles