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Keywords: PARP-1
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Journal Articles
J Cell Sci (2016) 129 (16): 3167–3177.
Published: 15 August 2016
...Simon Gemble; Géraldine Buhagiar-Labarchède; Rosine Onclercq-Delic; Denis Biard; Sarah Lambert; Mounira Amor-Guéret ABSTRACT Cytidine deaminase (CDA) deficiency induces an excess of cellular dCTP, which reduces basal PARP-1 activity, thereby compromising complete DNA replication, leading...
Includes: Supplementary data
Journal Articles
J Cell Sci (2001) 114 (20): 3771–3778.
Published: 15 October 2001
...Damien D’Amours; Frédéric R. Sallmann; Vishva M. Dixit; Guy G. Poirier Poly(ADP-ribosyl)ation is an important mechanism for the maintenance of genomic integrity in response to DNA damage. The enzyme responsible for poly(ADP-ribose) synthesis, poly(ADP-ribose) polymerase 1 (PARP-1), has been...