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Keywords: Oxygen sensing
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Journal Articles
J Cell Sci (2006) 119 (16): 3467–3480.
Published: 15 August 2006
... into the effects of iron and prolyl hydroxylase on oxygen sensing. The model advances quantitative molecular level understanding of HIF1 pathways - an endeavor that will help elucidate the diverse responses to hypoxia found in cancer, ischemia and exercise. HIF1 is a heterodimer, comprised of subunits HIF1α...
Includes: Supplementary data
Journal Articles
J Cell Sci (2003) 116 (7): 1319–1326.
Published: 1 April 2003
... hypoxic conditions. © The Company of Biologists Limited 2003 2003 Hypoxia Oxygen sensing Hypoxia inducible factor Hydroxylase The transcription factor hypoxia-inducible factor 1 (HIF-1) plays a central role in adaptation processes to reduced cellular oxygen availability( Semenza, 1999...