... and subsequent degradation . Mol. Cell. Biol. 30 , 1910 - 1922 . 10.1128/MCB.01089-09 Yang , S. and Wang , C. ( 2012 ). The intraflagellar transport protein IFT80 is required for cilia formation and osteogenesis . Bone 51 , 407 - 417 . 10.1016/j.bone.2012.06.021 Zhao...

... mutants were used to investigate the role of BMPR1A and BMPR1B in chondrogenesis and osteogenesis. We found that BMPR1A is necessary for chondrogenesis and osteogenesis, and BMPR1B prevents hypertrophy. GDF5 BMP2 M1673 Chondrogenesis Hypertrophy Osteogenesis Bone morphogenetic proteins...

... an immortalized human mesenchymal stromal cell (MSC) line model, we show that both N - and O-glycan processing in the Golgi functionally modulates early steps of osteogenic differentiation. We found that inhibiting O-glycan processing in the Golgi prior to the start of osteogenesis inhibited the mineralization...

... that modulate adhesion, cytoskeleton remodeling and differentiation. Although it is well recognized that stimuli for osteogenesis of mesenchymal stem cells (MSCs) drive FA maturation, actin organization and stress fiber polarization, the extent to which FA-mediated signals regulated by the FA protein...

... the architectural effects of the in vivo microenvironment and also for the therapeutic use of stem cells. * Author for correspondence ( [email protected] ) 14 10 2011 © 2012. 2012 Cell differentiation Mesenchymal stem cells Osteogenesis Nanotopography Surface functionalization...

..., such as dexamethasone, promote osteoblastic differentiation in several in vitro model systems. The mechanism by which these hormones induce osteogenesis remains poorly understood. We demonstrate here that the coordinate action of dexamethasone and the osteogenic transcription factor Runx2/Cbfa1 synergistically induces...

... with bone morphogenetic proteins (BMPs), a treatment that induces osteogenic differentiation, suggesting that MyoD has a role in BMP-induced osteogenesis of myogenic cells. This possibility is supported by our observations that muscle satellite cells derived from adult MyoD -/- mice show severely impaired...

... appeared as woven bone in polarized light microscopy. In essence, a bony collar had formed around a cartilage core, closely mimicking the events occurring during the early phases of endochondral ossification. Fig. 3. Osteogenesis in pellet cultures. BMSCs were cultured under chondrogenic...

[email protected] ) 11 9 2002 © The Company of Biologists Limited 2002 2002 Mouse embryonic stem cells Chondrogenesis Osteogenesis Mesenchymal cells Dedifferentiation Redifferentiation The development of the vertebrate skeleton is a multistep process that involves lineage...

..., 1992 ; Grzesik and Gehron-Robey, 1994 ). Pericyte Thrombospondin Osteogenesis Differentiation © 1996 by Company of Biologists 1996 25 08 1995 14 11 1995 * Author for correspondence REFERENCES Adams , J. C. and Lawler , J. ( 1993...

...Eleanor J. Mackie; Richard P. Tucker ABSTRACT The extracellular matrix glycoprotein, tenascin, is associated in vivo with mesenchyme undergoing osteogenesis and chondrogenesis, but is absent from mature bone and cartilage matrix. The expression of tenascin by osteoblastic cells in vitro has been...

..., demonstrate an inverse relationship between the differentiation of adipocytic and osteogenic cells in this culture system and are consistent with the possibility that the regulation of adipogenesis and osteogenesis can occur at the level of a common precursor in vivo . When cells were maintained throughout...

... of Biologists 1991 marrow adipocytes fibroblasts osteogenesis Cells with fibroblastic and adipocytic characteristics together with macrophages and endothelial cells are often included in descriptions of marrow stromal cell populations ( Dexter, 1982 ). Recently it has been proposed...

... 1990 23 07 1990 © 1990 by Company of Biologists 1990 pericytes osteogenesis differentiation calcification microvasculature Pericytes are defined by their location in vivo within the basement membrane of venules, arterioles and capillaries ( Kuwabara and Cogan, 1963...

... the possible development of in vitro clonal methods for the study of differentiation and regulation of the osteogenic and other fibroblastic cell lines of the marrow stromal system. 09 02 1987 01 04 1987 © 1987 by Company of Biologists 1987 marrow CFU-F clonal analysis osteogenesis...