... osmotic shock, p38γ in the cell nucleus increases its association with nuclear hDlg, thereby causing dissociation of hDlg-PSF complexes. Moreover, hDlg and PSF bind different RNAs; in response to osmotic shock, p38γ causes hDlg-PSF and hDlg-RNA dissociation independently of its kinase activity...

... protein was observed when cells had been exposed to osmotic shock or arsenite, indicating phosphorylation of Tau at multiple sites ( Fig. 2C ). We next examined whether endogenous Tau became phosphorylated at Thr50 in SH-SY5Y neuroblastoma cells exposed to osmotic shock, sodium arsenite or UV-C...

... keratins. There is a need for functional cell assays in which the impact of stress on intermediate filaments can be induced and analyzed. Using osmotic shock, we have induced cytoskeleton changes that suggest protective functions for actin and intermediate filament systems. Induction of the resulting...

... straightforward explanation for the differential effects of osmotic shock would be a role for dystrophin in mechanical stabilization of the cell membrane- cytoskeletal complex. On the basis of in situ studies on the diaphragm, Stedman et al. (1991) arrived at the conclusion that mature MDX muscle fibers within...