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Keywords: Oocytes
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Journal Articles
J Cell Sci (2019) 132 (18): jcs233379.
Published: 26 September 2019
... spindle assembly checkpoint (SAC) therefore has robust control over anaphase timing to prevent chromosome mis-segregation. Mammalian oocytes are prone to aneuploidy, the reasons for which remain obscure. In mitosis, Cep55 is required post-anaphase for the final steps of cytokinesis. We found that Cep55...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (14): jcs232330.
Published: 18 July 2019
...Federico Pelisch; Laura Bel Borja; Ellis G. Jaffray; Ronald T. Hay ABSTRACT Oocyte meiotic spindles in most species lack centrosomes and the mechanisms that underlie faithful chromosome segregation in acentrosomal meiotic spindles are not well understood. In C. elegans oocytes, spindle microtubules...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (24): 6030–6037.
Published: 15 December 2012
..., interpretation of the role of FZR1 during this period is hindered by the presence of maternal stores. In this study, therefore, we used an oocyte-specific knockout to examine FZR1 function in early mouse embryo development. Maternal FZR1 was not crucial for completion of meiosis, and furthermore viable pups were...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (6): 940–950.
Published: 15 March 2011
... the insoluble zona matrix and yet each protein traffics through oocytes without oligomerization. ZP2 and ZP3 were fluorescently tagged and molecular interactions were assayed by fluorescent complementation in CHO cells and growing oocytes. ZP2 and ZP3 traffic independently, but colocalize at the plasma membrane...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (14): 2446–2452.
Published: 15 July 2009
... that oocytes carrying an excess of two to three pairs of asynapsed homologous chromosomes fail to recruit enough BRCA1 to the asynapsed axes to activate MSUC. Furthermore, loss of MSUC function only transiently rescues oocytes from elimination during early postnatal development. The fact that the BRCA1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (8): 1330–1340.
Published: 15 April 2007
...Francisco J. Diaz; Karen Wigglesworth; John J. Eppig The two principal functions of ovarian follicles are developmental and endocrine. The cumulus cells surrounding the oocyte are specialized to serve the development of the oocyte and steroidogenesis is a principal role of mural granulosa cells...
Journal Articles
J Cell Sci (2005) 118 (11): 2393–2404.
Published: 1 June 2005
...François Prodon; Philippe Dru; Fabrice Roegiers; Christian Sardet The mature ascidian oocyte is a large cell containing cytoplasmic and cortical domains polarized along a primary animal-vegetal (a-v) axis. The oocyte cortex is characterized by a gradient distribution of a submembrane monolayer...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2005) 118 (2): 269–282.
Published: 15 January 2005
...Malgorzata Kloc; Laurence D. Etkin In many animals, normal development depends on the asymmetric distribution of maternal determinants, including various coding and noncoding RNAs, within the oocyte. The temporal and spatial distribution of localized RNAs is determined by intricate mechanisms...
Journal Articles
J Cell Sci (2004) 117 (26): 6289–6296.
Published: 15 December 2004
... eggs of other species so far described have APC cdc20 activity only. Both of the two main APC/C activators, cdc20 and cdh1, were present in mouse eggs at MII ( Fig. 1 ). We also observed these proteins in oocytes at all stages of the first meiotic division (not shown). The fact that mouse eggs...
Journal Articles
J Cell Sci (2004) 117 (25): 6095–6104.
Published: 1 December 2004
... in amphibian oocytes induces the formation of intranuclear membrane structures that form extensive arrays of stacked cisternae. These `lamin membrane arrays' are attached to the inner nuclear membrane but are not continuous with it. Induction of this membrane proliferation depends on CaaX-specific...
Journal Articles
J Cell Sci (1989) 1989 (Supplement_12): 253–275.
Published: 1 February 1989
...). The centrosomes of animal cells typically consist of a pair of orthogonally arranged centrioles surrounded by osmiophilic, fibro-granular material called the pericentrio- Key words: centrosome, cell cycle, microtubule, mitosis, spindle, centrioles, division, sea urchin, oocytes, mercaptoethanol, Colcemid. 254 G...