...Rafael Lucena; Akshi Jasani; Steph Anastasia; Douglas Kellogg; Maria Alcaide-Gavilan ABSTRACT Tor kinases play diverse and essential roles in control of nutrient signaling and cell growth. These kinases are assembled into two multiprotein complexes known as TORC1 and TORC2. In budding yeast, TORC2...

..., regulate microbial virulence programs and factors, limit microbial access to nutrient sources and generate toxic environments for microbes. Collectively, the studies described here support a critical role for the rewiring of cellular metabolism in the defense against microbes. Further study of host...

...), mediates TOR action . Cell   110 , 177 - 189 . 10.1016/S0092-8674(02)00833-4 Hosokawa , N. , Hara , T. , Kaizuka , T. , Kishi , C. , Takamura , A. , Miura , Y. , Iemura , S. , Natsume , T. , Takehana , K. , Yamada , N. , et al. (2009). Nutrient...

... screen of Drosophila larvae for fat-storage mutants reveals a role for Sir2 in coupling fat storage to nutrient availability.   PLoS Genet.   6 , e1001206 . 10.1371/journal.pgen.1001206 Reusch   J. E. , Colton   L. A. , Klemm   D. J. (2000). CREB activation induces adipogenesis in 3T3...