...: DDX19 plays a crucial role in mRNA export at the nuclear pore complex. We find that SUMOylation enriches DDX19 at the nuclear envelope, facilitates its interaction with Gle1 and modulates the mRNA export function. mRNA export SUMO DDX19 Nup358 Gle1 Department of Biotechnology http...

...Yuki Ogawa; Matthew N. Rasband ABSTRACT Ranbp2 (also known as Nup358) is a member of the nucleoporin family, which constitutes the nuclear pore complex. Ranbp2 localizes at the nuclear membrane and was recently reported at the axon initial segment (AIS). However, we show that the anti-Ranbp2...

...Bouchra Khalaf; Alessandro Roncador; Francesca Pischedda; Antonio Casini; Sabine Thomas; Giovanni Piccoli; Michael Kiebler; Paolo Macchi ABSTRACT Nup358 (also known as RanBP2) is a member of the large nucleoporin family that constitutes the nuclear pore complex. Depending on the cell type...

... regulates elongation of microridges by controlling levels of apical Lgl, which acts as a pro-elongation factor. Here, we show that the nucleoporin Nup358 (also known as RanBP2) – a component of the nuclear pore complex and a part of cytoplasmic annulate lamellae (AL) – SUMOylates zebrafish aPKC. Nup358...

... in concert with the canonical α-tubulin acetyltransferase αTAT1. Finally, we show that this regulation is dependent on the RAN-binding protein 2 (RanBP2), a component of nuclear pore complexes also known as Nup358, which facilitates the interaction of GCN5L1 with α-tubulin. This study identifies a novel...

... microtubule plus-end-targeting function, suggesting an additional microtubule-binding mode for APC. Through the same region, APC interacts with Nup358 (also called RanBP2), a microtubule-binding nucleoporin. Ectopic expression of the middle region of APC is sufficient to recruit endogenous Nup358 to the plus...

...Saskia Hutten; Sarah Wälde; Christiane Spillner; Joachim Hauber; Ralph H. Kehlenbach Nup358 (also known as RanBP2), a component of the cytoplasmic filaments of the nuclear pore complex, has been implicated in various nucleocytoplasmic transport pathways. Here, we identify Nup358 as an important...