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Keywords: Nucleoskeleton
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Journal Articles
In collection:
Mechanobiology
J Cell Sci (2017) 130 (14): 2243–2250.
Published: 15 July 2017
..., and chromatin in particular, respond to changes in the mechanical microenvironment of the cell, resulting in architectural and transcriptional alterations, and thereby facilitating cellular adaption. Mechanotransduction Nucleus Nuclear lamina Nucleoskeleton Nuclear mechanical response Cells...
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2017) 130 (14): 2243–2250.
Published: 15 July 2017
..., and chromatin in particular, respond to changes in the mechanical microenvironment of the cell, resulting in architectural and transcriptional alterations, and thereby facilitating cellular adaption. Mechanotransduction Nucleus Nuclear lamina Nucleoskeleton Nuclear mechanical response Max...
Journal Articles
J Cell Sci (2014) 127 (18): 3956–3969.
Published: 15 September 2014
... The authors declare no competing interests. 18 12 2013 8 07 2014 © 2014. Published by The Company of Biologists Ltd 2014 Barrier to autointegration factor Emerin Emery-Dreifuss muscular dystrophy Lamin LEM domain Nestor-Guillermo progeria Nuclear envelope Nucleoskeleton...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (14): 3005–3015.
Published: 15 July 2014
.... Published by The Company of Biologists Ltd 2014 Cell mechanics Mechanotransduction Extra-cellular matrix Nucleus Nucleoskeleton Proteostasis Evolution has likely driven our tissues and organs to fulfill their roles with optimal efficiency and, of course, viability. Mature tissues need...
Journal Articles
J Cell Sci (2009) 122 (10): 1551–1562.
Published: 15 May 2009
...., Raymond, Y. and Cook, P. R. ( 1995 ). Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells. J. Cell Sci. 108 , 635 -644. Jackson, D. A. and Cook, P. R. ( 1985 ). Transcription occurs at a nucleoskeleton. EMBO J. 4 , 919 -925. Jackson, D...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2005) 118 (2): 409–420.
Published: 15 January 2005
... myogenesis, Rb was rapidly and progressively dephosphorylated. Underphosphorylated Rb formed complexes with LAP2α in proliferating myoblasts and postmitotic myoblasts. In myoblasts transfected with the mutant lamins, this complex was disrupted. These data suggest that remodelling of the nucleoskeleton...
Journal Articles
J Cell Sci (2003) 116 (9): 1733–1743.
Published: 1 May 2003
... morphology in male meiosis. We propose that EAST constitutes a component of a nucleoskeleton that helps to constrain the mobility of chromosomes in interphase, mitosis and meiosis. Fig. 5. Loss of east leads to abnormal movements of chromosomes during prometaphase. Time-lapse recordings of cell...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (1998) 111 (24): 3663–3673.
Published: 18 December 1998
...J. Miguel Ortega; Melvin L. DePamphilis ABSTRACT To determine whether or not initiation sites for DNA replication in mammalian cells are defined by association with nuclear structure, attachments between the nucleoskeleton and the hamster DHFR gene initiation zone were examined. Nucleoskeletons...
Journal Articles
J Cell Sci (1995) 1995 (Supplement_19): 59–65.
Published: 1 January 1995
... The Company of Biologists Limited 1995 1995 nucleoskeleton replication transcription repair chromatin loop Compared to the compartmentation found within the cytoplasm, the nucleus has traditionally been viewed as relatively unstructured. However, recent experiments suggest that it also has...
Journal Articles
J Cell Sci (1994) 107 (8): 2191–2202.
Published: 1 August 1994
... sections from which ∼90% chromatin had been removed showed that most DNA synthesis occurs in specific dense structures (replication factories) attached to a diffuse nucleoskeleton. These factories appear at the end of G 1 -phase and quickly become active; as S-phase progresses, they increase in size...
Journal Articles
Journal Articles
J Cell Sci (1994) 107 (3): 469–486.
Published: 1 March 1994
... and nucleosome assembly, and may reflect the attachment of the yeast DNA to the rodent cell nucleoskeleton. The yeast integrant replicates late in S phase at a time when G bands of the mouse chromosomes are being replicated, and participates in sister chromatid exchanges at a high frequency. We discuss...
Journal Articles
J Cell Sci (1994) 107 (2): 639–648.
Published: 1 February 1994
.... These results suggest that the dense fibrillar component is the site of rRNA transcription. After dispersing the granular component and the dense fibrillar component by a hypotonic treatment, removal of most chromatin and preparation of resinless sections, fibrillar centres remained fixed to a nucleoskeleton...
Journal Articles
J Cell Sci (1993) 105 (2): 541–550.
Published: 1 June 1993
... was very stable. Foci remained when ∼90% chromatin was removed, suggesting they were attached to an underlying structure. * Author for correspondence 22 01 1993 24 02 1993 © 1993 by Company of Biologists 1993 replication foci DNA polymerase nucleoskeleton dTTP analogues...
Journal Articles
Journal Articles
J Cell Sci (1988) 90 (3): 365–378.
Published: 1 July 1988
..., but their chromatin is accessible to restriction enzymes and so probably to most enzymes used in molecular biology. We hope that these encapsulated derivatives of cells, well-preserved and containing intact DNA, cytoskeleton and nucleoskeleton, accessible, yet expressing in vitro the major nuclear functions...