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Keywords: Nuclear envelope
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J Cell Sci (2023) 136 (7): jcs260155.
Published: 27 March 2023
...Hanna Thoma; Luisa Grünewald; Silke Braune; Elisabeth Pasch; Manfred Alsheimer ABSTRACT SUN domain proteins are conserved proteins of the nuclear envelope and key components of the LINC complexes (for ‘linkers of the nucleoskeleton and the cytoskeleton’). Previous studies have demonstrated...
Includes: Supplementary data
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J Cell Sci (2022) 135 (8): jcs259493.
Published: 3 May 2022
... calibration of nuclear stiffness. Cancer Metastasis Cell migration Cytoskeleton Nucleus Nuclear envelope Emerin Src Mechanotransduction Melanoma Research Alliance http://dx.doi.org/10.13039/100005190 688232 American Cancer Society http://dx.doi.org/10.13039/100000048...
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J Cell Sci (2021) 134 (12): jcs258194.
Published: 21 June 2021
...Zeinab Jahed; Nya Domkam; Jessica Ornowski; Ghafar Yerima; Mohammad R. K. Mofrad ABSTRACT Large protein complexes assemble at the nuclear envelope to transmit mechanical signals between the cytoskeleton and nucleoskeleton. These protein complexes are known as the linkers of the nucleoskeleton...
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J Cell Sci (2020) 133 (20): jcs242172.
Published: 30 October 2020
... in interphase and becomes dumbbell shaped during mitotic division to facilitate the transfer of one nucleus to the daughter cell. Because yeast cells undergo closed mitosis, the nuclear envelope remains intact throughout the cell cycle. The pathways that regulate nuclear shape are not well characterized...
Includes: Supplementary data
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J Cell Sci (2020) 133 (16): jcs246546.
Published: 17 August 2020
... DNA, histones and various other nuclear proteins, including those enriched at the nuclear envelope, BAF appears to be essential for replicating cells to protect the genome and enable cell division. Cellular processes, such as innate immunity, post-mitotic nuclear reformation, repair of interphase...
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J Cell Sci (2020) 133 (6): jcs238527.
Published: 26 March 2020
... in glycosylphosphatidylinositol (GPI), localizes to the nuclear envelope (NE). Although this NE localization is essential for Drosophila development, the underlying molecular mechanism remains unknown. To elucidate this mechanism, we identified PIG-B-interacting proteins by performing immunoprecipitation followed by proteomic...
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J Cell Sci (2019) 132 (14): jcs229245.
Published: 15 July 2019
..., the nuclear envelope possesses unique mechanical properties, which enables it to resist cytoskeletal forces. Here, we review studies that are beginning to provide quantitative insights into nuclear membrane mechanics. We discuss how the mechanical properties of the fused nuclear membranes mediate...
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J Cell Sci (2018) 131 (20): jcs218024.
Published: 26 October 2018
..., is synthesized by the PIG enzymes. Most PIGs are localized to the endoplasmic reticulum (ER), but Drosophila PIG-B (DmPIG-B) is localized to the nuclear envelope (NE). To determine whether the NE localization of DmPIG-B is functionally important, we defined the determinants of localization and generated an ER...
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J Cell Sci (2018) 131 (18): jcs217513.
Published: 20 September 2018
...: Nuclei are highly branched throughout the heterogeneous population of healthy epidermal cells in the Xenopus tail fin periphery, and disruption of nuclear branching results in improper fin morphology. Nuclear morphology Nuclear envelope Lamin Actin Xenopus tropicalis Epidermis...
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J Cell Sci (2018) 131 (14): jcs203653.
Published: 20 July 2018
... approaches used in comparative biology studies. Chromosome segregation Comparative biology Evolution Mitosis Nuclear envelope Spindle Wellcome Trust 10.13039/100010269 103741/Z/14/Z The generality of cell biological mechanisms has become a go-to argument for researchers...
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J Cell Sci (2017) 130 (10): 1822–1834.
Published: 15 May 2017
... contrast, all Y-complex components identified so far exhibit distinctively biased localization to the MIC nuclear envelope (NE) compared to the MAC NE ( Fig. 3 B). Fluorescence intensities in the MIC were 2.69–3.96 times higher than those in the MAC ( Fig. 3 B). This biased localization of Y-complex...
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J Cell Sci (2017) 130 (2): 444–452.
Published: 15 January 2017
...Marta G. Lete; Richard D. Byrne; Alicia Alonso; Dominic Poccia; Banafshé Larijani ABSTRACT Regulation of nuclear envelope dynamics is an important example of the universal phenomena of membrane fusion. The signalling molecules involved in nuclear membrane fusion might also be conserved during...
Includes: Supplementary data