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Keywords: Nonsense-mediated decay
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Journal Articles
J Cell Sci (2004) 117 (24): 5713–5720.
Published: 15 November 2004
... of nuclear mRNAs containing premature termination codons by nonsense-mediated decay (NMD). Only ribosomes can detect termination codons, and as some NMD occurs within the nuclear fraction, active nuclear ribosomes could perform the required detection. The second evidence is the demonstration that tagged...
Journal Articles
J Cell Sci (2002) 115 (15): 3033–3038.
Published: 01 August 2002
... that they are suitable for translation. mRNA surveillance facilitates the detection and destruction of mRNAs that contain premature termination codons by a process called nonsense-mediated decay. Moreover, recent studies have shown that a distinct mRNA surveillance process, called nonstop decay, is responsible...