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J Cell Sci (2017) 130 (13): 2134–2146.
Published: 01 July 2017
...Joerg Isensee; Cosimo Schild; Frank Schwede; Tim Hucho ABSTRACT Maturation of nociceptive neurons depends on changes in transcription factors, ion channels and neuropeptides. Mature nociceptors initiate pain in part by drastically reducing the activation threshold via intracellular sensitization...
Includes: Supplementary data
Joerg Isensee, Mandy Diskar, Steffen Waldherr, René Buschow, Jan Hasenauer, Anke Prinz, Frank Allgöwer, Friedrich W. Herberg, Tim Hucho
J Cell Sci (2014) 127 (1): 216–229.
Published: 01 January 2014
... primary cells has not been investigated in detail. Using a high content screening microscopy approach, we identified the RIIβ subunit of PKA-II to be predominantly expressed in a subgroup of sensory neurons. The RIIβ-positive subgroup included most neurons expressing nociceptive markers (TRPV1, NaV1.8...
J Cell Sci (2007) 120 (16): 2864–2874.
Published: 15 August 2007
... Biologists Limited 2007 2007 Sbr I/II SNAP25 Syntaxin I Nociception Trigeminal ganglion Capsaicin Bradykinin Pain of various kinds (nociceptive, neuropathic, inflammatory) pose substantial medical challenges, with 21% of worldwide adults suffering from persistent pain (WHO report 2004). A...