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Keywords: Neutrophils
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Journal Articles
J Cell Sci (2021) 134 (5): jcs252403.
Published: 8 March 2021
... immune cell response by co-culturing infected organoids with neutrophils, and determined that effectors like CPAF (also known as CT858) and TepP (also known as CT875) limit the recruitment of neutrophils to infected organoids. Collectively, our model can be applied to study the cell biology of Chlamydia...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (19): jcs235838.
Published: 12 October 2020
... that topical insulin application could reverse the impaired inflammation reaction in the diabetic wound environment and promote healing of diabetic wounds. Our study revealed that insulin promoted apoptosis of neutrophils and subsequently triggered polarization of macrophages. Both in vivo and in vitro studies...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2018) 131 (18): jcs217422.
Published: 21 September 2018
...Bhagawat C. Subramanian; Konstadinos Moissoglu; Carole A. Parent ABSTRACT Neutrophils sense and respond to diverse chemotactic cues through G-protein-coupled receptors (GPCRs). However, the precise trafficking dynamics of chemoattractant GPCRs during neutrophil activation and chemotaxis remain...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (9): 1831–1842.
Published: 1 May 2016
... with four members FAM3A, FAM3B, FAM3C and FAM3D. In this study, we found that FAM3D strongly chemoattracted human peripheral blood neutrophils and monocytes. To identify the FAM3D receptor, we used chemotaxis, receptor internalization, Ca 2+ flux and radioligand-binding assays in FAM3D-stimulated HEK293...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (20): 4627–4635.
Published: 15 October 2013
...Sharon Dewitt; Robert J. Francis; Maurice B. Hallett Summary Following adherence of neutrophils to the endothelium, neutrophils undergo a major morphological change that is a necessary prelude to their extravasation. We show here that this shape change is triggered by an elevation of cytosolic...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (18): 4077–4084.
Published: 15 September 2013
... advantage of the genetic tractability and translucency of zebrafish larvae to first characterise how a null mutant in zfWASp influences the behaviour of neutrophils and macrophages in response to tissue damage and to clearance of infections. We then use this mutant background to study how leukocyte lineage...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (18): 3053–3059.
Published: 15 September 2011
...Emma Colucci-Guyon; Jean-Yves Tinevez; Stephen A. Renshaw; Philippe Herbomel The early control of potentially invading microbes by our immune system primarily depends on its main professional phagocytes – macrophages and neutrophils. Although the different functions of these two cell types have...
Includes: Multimedia, Supplementary data
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J Cell Sci (2003) 116 (17): 3471–3478.
Published: 1 September 2003
.... * Author for correspondence (e-mail: [email protected] ) © The Company of Biologists Limited 2003 2003 Chemotaxis Dictyostelium PI 3-kinase Fibroblasts Neutrophils Actin Chemotaxis, movement of a cell towards a chemoattractant signal, is a fundamental process involved in a wide...
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J Cell Sci (1993) 106 (2): 441–452.
Published: 1 October 1993
... endothelial cells and migration across the endothelium. A number of factors govern the interactions between leukocytes and endothelial cells, including the expression of molecules on the surface of activated leukocytes and/or endothelial cells, certain products of neutrophil activation, and shear forces...
Journal Articles
J Cell Sci (1993) 106 (2): 493–501.
Published: 1 October 1993
...Alexandra Volz ABSTRACT The study analyses the distribution and quantitative expression of surface CD18 of neutrophils exposed to distinct stimuli that produce different types of continuous shape changes, including types that are associated with locomotion and others that are not. The chemotactic...
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J Cell Sci (1992) 101 (2): 403–414.
Published: 1 February 1992
...Banu Yürüker; Verena Niggli ABSTRACT We have studied the reorganization of vinculin and α-actinin during the process of adhesion in human neutrophils using immunofluorescence microscopy and interference reflection microscopy (IRM). Neutrophils in contact with uncoated glass formed black IRM areas...