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Keywords: Neonatal Fc receptor
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Journal Articles
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Membrane Trafficking
J Cell Sci (2023) 136 (15): jcs260912.
Published: 11 August 2023
...Andreas Pannek; Janine Becker-Gotot; Steven K. Dower; Anne M. Verhagen; Paul A. Gleeson ABSTRACT Human serum albumin (HSA) has a long circulatory half-life owing, in part, to interaction with the neonatal Fc receptor (FcRn or FCGRT) in acidic endosomes and recycling of internalised albumin...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (5): jcs235416.
Published: 1 October 2019
...Wei Hong Toh; Jade Louber; Ismail S. Mahmoud; Jenny Chia; Greg T. Bass; Steve K. Dower; Anne M. Verhagen; Paul A. Gleeson; Ana-Maria Lennon-Duménil ABSTRACT The neonatal Fc receptor (FcRn) rescues albumin and IgG from degradation following endocytosis and thereby extends the half-life...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2001) 114 (8): 1591–1598.
Published: 15 April 2001
...Kevin M. McCarthy; Michael Lam; Laura Subramanian; Reena Shakya; Zhen Wu; Estelle E. Newton; Neil E. Simister ABSTRACT The neonatal Fc receptor, FcRn, transports immunoglobulin G (IgG) across intestinal epithelial cells of suckling rats and mice from the lumenal surface to the serosal surface...