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Keywords: Neomycin
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Journal Articles
J Cell Sci (2006) 119 (10): 2084–2094.
Published: 15 May 2006
.... ‡ Authors for correspondence (e-mail: gerald.hammond@cancer.org.uk ; giampietro.schiavo@cancer.org.uk ) * Present address: Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK Diacylglycerol Exocytosis Neomycin Phosphoinositide Phospholipase C...
Includes: Supplementary data
Journal Articles
J Cell Sci (2003) 116 (12): 2519–2530.
Published: 15 June 2003
... was lost after mutation of potential PtdIns(4,5) P 2 -binding motifs. Moreover, neomycin, which masks PtdIns(4,5) P 2 polar heads, was shown to decrease by 50% the association of PTPL1 with the cytoskeletal fraction. These results identify the crucial role of the FERM domain in PTPL1 intracellular...
Journal Articles
J Cell Sci (2002) 115 (12): 2569–2580.
Published: 15 June 2002
... with epidermal growth factor. In certain types of kidney-derived cells such as MDCK cells, however, ERM proteins appear to be activated in the absence of Rho activation and remain active without C-terminal phosphorylation. Interestingly, microinjection of an aminoglycoside antibiotic, neomycin, which binds...
Journal Articles
J Cell Sci (1991) 98 (2): 159–168.
Published: 1 February 1991
...PAUL M. LARSEN; TUNG-LING L. CHEN; STEPHEN M. WOLNIAK Neomycin has been reported to inhibit polyphosphoinositide cycling by preventing the hydrolysis of phosphatidylinositol 4,5-bisphosphate into inositol 1,4,5-trisphosphate and 1,2-diacylglycerol. Inositol 1,4,5-trisphosphate, through...