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1-5 of 5
Keywords: NMDA receptor
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Journal Articles
Steven L. Gonias, Michael A. Banki, Andrew S. Gilder, Pardis Azmoon, Wendy M. Campana, Elisabetta Mantuano
Journal:
Journal of Cell Science
J Cell Sci (2018) 131 (14): jcs217083.
Published: 26 July 2018
... inhibits the effects of tissue-type plasminogen activator on cell signaling and physiology mediated by the NMDA receptor. The mechanism of PAI1 activity involves targeting of tPA to the endocytic receptor LRP1. Tissue-type plasminogen activator Plasminogen activator inhibitor-1 NMDA receptor LDL...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2015) 128 (18): 3478–3488.
Published: 15 September 2015
...Elisabetta Mantuano; Michael S. Lam; Masataka Shibayama; W. Marie Campana; Steven L. Gonias ABSTRACT NMDA receptors (NMDA-Rs) are ionotropic glutamate receptors, which associate with LDL-receptor-related protein-1 (LRP1) to trigger cell signaling in response to protein ligands in neurons. Here, we...
Journal Articles
Ishwar Gill, Sammy Droubi, Silvia Giovedi, Karlie N. Fedder, Luke A. D. Bury, Federica Bosco, Michael P. Sceniak, Fabio Benfenati, Shasta L. Sabo
Journal:
Journal of Cell Science
J Cell Sci (2015) 128 (4): 768–780.
Published: 15 February 2015
...Ishwar Gill; Sammy Droubi; Silvia Giovedi; Karlie N. Fedder; Luke A. D. Bury; Federica Bosco; Michael P. Sceniak; Fabio Benfenati; Shasta L. Sabo ABSTRACT During cortical development, N-methyl-D-aspartate (NMDA) receptors (NMDARs) facilitate presynaptic terminal formation, enhance neurotransmitter...
Includes: Supplementary data
Journal Articles
Karim Benchenane, Hervé Castel, Michel Boulouard, Rosemarie Bluthé, Monica Fernandez-Monreal, Benoit D. Roussel, José P. Lopez-Atalaya, Sabrina Butt-Gueulle, Véronique Agin, Eric Maubert, Robert Dantzer, Omar Touzani, François Dauphin, Denis Vivien, Carine Ali
Journal:
Journal of Cell Science
J Cell Sci (2007) 120 (4): 578–585.
Published: 15 February 2007
... receptor signalling strategically controls crucial brain functions. This process depends on several ligands and modulators, one of which unexpectedly includes the serine protease tissue-type plasminogen activator (tPA). In vitro, tPA increases NMDA-receptor-mediated calcium influx by interacting...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2003) 116 (13): 2665–2675.
Published: 1 July 2003
...) raised[Ca 2+ ] c mainly by activating metabotropic glutamate receptors (mGluR), whereas at high concentrations (>10 μM) it raised[Ca 2+ ] c mainly by activating AMPA/kainate receptors. The contribution of NMDA receptors to the glutamate-mediated[Ca 2+ ] c rises was largest at intermediate...