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Keywords: NIMA
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Journal Articles
J Cell Sci (2013) 126 (15): 3344–3355.
Published: 1 August 2013
... is completed, the daughter buds form around the duplicated centrosomes and subsequently elongate to serve as the scaffold for organellogenesis and organelle partitioning. The molecular control mechanism of this process is poorly understood. Here, we characterized a T. gondii NIMA-related kinase (Nek) ortholog...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (19): 4423–4433.
Published: 1 October 2012
...Andrew M. Fry; Laura O'Regan; Sarah R. Sabir; Richard Bayliss Summary Genetic screens for cell division cycle mutants in the filamentous fungus Aspergillus nidulans led to the discovery of never-in-mitosis A (NIMA), a serine/threonine kinase that is required for mitotic entry. Since that discovery...
Journal Articles
J Cell Sci (2009) 122 (13): 2274–2282.
Published: 1 July 2009
...Jufang Chang; Robert H. Baloh; Jeffrey Milbrandt NIMA-related kinases (Neks) belong to a large family of Ser/Thr kinases that have critical roles in coordinating microtubule dynamics during ciliogenesis and mitotic progression. The Nek kinases are also expressed in neurons, whose axonal projections...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2005) 118 (22): 5161–5169.
Published: 15 November 2005
... eukaryotic Neks, although not strictly orthologs of their vertebrate counterparts, can provide clues to ancestral functions that might be retained in the vertebrate Neks. Relatives of the Nek2/NIMA proteins play important roles at the G2-M transition in nuclear envelope breakdown and centromere separation...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (1998) 111 (7): 967–976.
Published: 1 April 1998
...Michael J. E. Krien; Sarah J. Bugg; Manuela Palatsides; Gigi Asouline; Mitsuoki Morimyo; Matthew J. O’Connell ABSTRACT Entry into mitosis requires p34cdc 2 , which activates downstream mitotic events through phosphorylation of key target proteins. In Aspergillus nidulans , the NIMA protein kinase...
Journal Articles
J Cell Sci (1997) 110 (17): 2013–2025.
Published: 1 September 1997
... could not generate the MPM-2 phosophoepitope. However, bacterially expressed NIMA from Aspergillus and ultracentrifuged mitotic HeLa cell extract were able to catalyze the rephosphorylation of the MPM-2 epitope at kinetochores. Furthermore, fractionation of mitotic HeLa cell extract showed that kinases...