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Keywords: NIMA
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Journal Articles
J Cell Sci (2013) 126 (15): 3344–3355.
Published: 01 August 2013
... is completed, the daughter buds form around the duplicated centrosomes and subsequently elongate to serve as the scaffold for organellogenesis and organelle partitioning. The molecular control mechanism of this process is poorly understood. Here, we characterized a T. gondii NIMA-related kinase (Nek) ortholog...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (19): 4423–4433.
Published: 01 October 2012
...Andrew M. Fry; Laura O'Regan; Sarah R. Sabir; Richard Bayliss Summary Genetic screens for cell division cycle mutants in the filamentous fungus Aspergillus nidulans led to the discovery of never-in-mitosis A (NIMA), a serine/threonine kinase that is required for mitotic entry. Since that discovery...
Journal Articles
J Cell Sci (2009) 122 (13): 2274–2282.
Published: 01 July 2009
...Jufang Chang; Robert H. Baloh; Jeffrey Milbrandt NIMA-related kinases (Neks) belong to a large family of Ser/Thr kinases that have critical roles in coordinating microtubule dynamics during ciliogenesis and mitotic progression. The Nek kinases are also expressed in neurons, whose axonal projections...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (23): 3912–3921.
Published: 01 December 2008
...Joseph Rapley; Marta Nicolàs; Aaron Groen; Laura Regué; M. Teresa Bertran; Carme Caelles; Joseph Avruch; Joan Roig Nek6 and Nercc1 (also known as Nek9) belong to the NIMA family of protein kinases. Nercc1 is activated in mitosis, whereupon it binds, phosphorylates and activates Nek6. Interference...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (22): 5161–5169.
Published: 15 November 2005
... eukaryotic Neks, although not strictly orthologs of their vertebrate counterparts, can provide clues to ancestral functions that might be retained in the vertebrate Neks. Relatives of the Nek2/NIMA proteins play important roles at the G2-M transition in nuclear envelope breakdown and centromere separation...
Journal Articles
J Cell Sci (2002) 115 (8): 1759–1768.
Published: 15 April 2002
...Moe R. Mahjoub; Ben Montpetit; Lifan Zhao; Rip J. Finst; Benjamin Goh; Apollos C. Kim; Lynne M. Quarmby The NIMA kinases are one of several families of kinases that participate in driving the eukaryotic cell cycle. NIMA-related kinases have been implicated in G2/M progression, chromatin...