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Keywords: NADPH oxidaseClose
George Damoulakis, Laure Gambardella, Kent L. Rossman, Campbell D. Lawson, Karen E. Anderson, Yoshinori Fukui, Heidi C. Welch, Channing J. Der, Len R. Stephens, Phillip T. Hawkins
J Cell Sci (2014) 127 (11): 2589–2600.
Published: 01 June 2014
...-dependent NADPH oxidase activity, suggesting they both function upstream of Rac in this system. Loss of RhoG also impaired GPCR-driven recruitment of the Rac GEF DOCK2, and F-actin, to the leading edge of migrating neutrophils. Taken together, our results reveal a new signalling hierarchy in which P-Rex1...
J Cell Sci (2012) 125 (4): 956–964.
Published: 15 February 2012
... that it promotes angiogenic responses in endothelial cells, although the underlying signalling mechanisms are unclear. Reactive oxygen species derived from NADPH oxidases are major signalling molecules in the vasculature. Because NOX2 is functional in endothelial cells, we investigated the role of the NOX2...
Includes: Supplementary data
J Cell Sci (2009) 122 (8): 1238–1247.
Published: 15 April 2009
...Sylvia Luxen; Deborah Noack; Monika Frausto; Suzel Davanture; Bruce E. Torbett; Ulla G. Knaus Duox NADPH oxidases generate hydrogen peroxide at the air-liquid interface of the respiratory tract and at apical membranes of thyroid follicular cells. Inactivating mutations of Duox2 have been linked...
Includes: Multimedia, Supplementary data
Martina Buggisch, Bernadette Ateghang, Carola Ruhe, Catrin Strobel, Sabine Lange, Maria Wartenberg, Heinrich Sauer
J Cell Sci (2007) 120 (5): 885–894.
Published: 01 March 2007
... and 2-mercaptoglycin (NMPG). In ES cells ROS induced expression of the cardiac-specific genes encoding α-actin, β-MHC, MLC2a, MLC2v and ANP as well as the transcription factors GATA-4, Nkx-2.5, MEF2C, DTEF-1 and the growth factor BMP-10. During differentiation ES cells expressed the NADPH oxidase...
Sylvie Elsen, Jacques Doussière, Christian L. Villiers, Mathias Faure, Rolande Berthier, Anne Papaioannou, Nathalie Grandvaux, Patrice N. Marche, Pierre V. Vignais
J Cell Sci (2004) 117 (11): 2215–2226.
Published: 01 May 2004
...Sylvie Elsen; Jacques Doussière; Christian L. Villiers; Mathias Faure; Rolande Berthier; Anne Papaioannou; Nathalie Grandvaux; Patrice N. Marche; Pierre V. Vignais All the components of the O 2 – -generating NADPH oxidase typically found in neutrophils, namely a membrane-bound low potential...
J Cell Sci (2003) 116 (15): 3221–3226.
Published: 01 August 2003
...Jennifer L. Bankers-Fulbright; Gerald J. Gleich; Gail M. Kephart; Hirohito Kita; Scott M. O'Grady Protein kinase C (PKC) activation in human eosinophils increases NADPH oxidase activity, which is associated with plasma membrane depolarization. In this study, membrane potential measurements...
J Cell Sci (2002) 115 (6): 1099–1105.
Published: 15 March 2002
... of the neutrophil oxidase complex. * Author for correspondence (e-mail: email@example.com ) © The Company of Biologists Limited 2002 2002 Phox PI3-kinase PtdIns(3) P Trafficking NADPH oxidase SNX Phosphoinositide levels are exquisitely regulated within cells and constitute...