...Henriette Aksnes; Nina McTiernan; Thomas Arnesen ABSTRACT Most proteins receive an acetyl group at the N terminus while in their nascency as the result of modification by co-translationally acting N-terminal acetyltransferases (NATs). The N-terminal acetyl group can influence several aspects...

... of internal lysine residues (lysine acetylation) or acetylation of the α-amino group at the N-terminal amino acid residue (N-terminal acetylation). Although the former modification is considered a classic epigenetic mark, the biological importance of N-terminal acetylation has been mostly overlooked...

...Alexander J. Polino; Muhammad M. Hasan; Katherine Floyd; Yolotzin Avila-Cruz; Yujuan Yang; Daniel E. Goldberg ABSTRACT N-terminal acetylation is a common eukaryotic protein modification that involves the addition of an acetyl group to the N-terminus of a polypeptide. This modification is largely...

... periphery, suggesting a role for Arl8a and Arl8b as positive regulators of lysosomal transport. * Author for correspondence (e-mail: [email protected] ) 24 2 2006 © The Company of Biologists Limited 2006 2006 Arf family GTPase Lysosome N-terminal acetylation...