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Keywords: N-myristoylation
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Journal Articles
HIV-1 N-myristoylation-dependent hijacking of late endosomes/lysosomes to drive Gag assembly in macrophages
Open AccessGabriel I. Guajardo-Contreras, Ana L. Abdalla, Alex Chen, Meijuan Niu, Erwan Beauchamp, Luc G. Berthiaume, Alan W. Cochrane, Andrew J. Mouland
Journal:
Journal of Cell Science
J Cell Sci (2024) 137 (22): jcs263588.
Published: 21 November 2024
... VCC formation in both the THP-1 cell line and primary macrophages. In conclusion, we present evidence supporting the idea that HIV-1 manipulates the LEL trajectory to guide Gag to VCCs in an N-myristoylation-dependent manner. * Author for correspondence ( [email protected] ) Handling...
Includes: Supplementary data
Journal Articles
Mouse Stbd1 is N -myristoylated and affects ER–mitochondria association and mitochondrial morphology
Open AccessIn collection:
Organelles
Anthi Demetriadou, Julia Morales-Sanfrutos, Marianna Nearchou, Otto Baba, Kyriacos Kyriacou, Edward W. Tate, Anthi Drousiotou, Petros P. Petrou
Journal:
Journal of Cell Science
J Cell Sci (2017) 130 (5): 903–915.
Published: 1 March 2017
... regions of close apposition between the ER and mitochondria. We demonstrate that N -myristoylation and binding of Stbd1 to glycogen act as major determinants of its subcellular targeting. Moreover, overexpression of non-myristoylated Stbd1 enhanced the association between ER and mitochondria, and further...
Includes: Supplementary data
